Физические упражнения как эффективная адъювантная терапия при ремиссии воспалительных заболеваний кишечника (обзор литературы)
https://doi.org/10.33878/2073-7556-2024-23-1-152-161
Аннотация
Воспалительные заболевания кишечника (ВЗК) включают болезнь Крона и язвенный колит. ВЗК являются хроническими болезнями с траекторией ремиссии и рецидива. Медикаментозная терапия ВЗК недостаточно эффективна. Существует потребность в адъювантной терапии ВЗК. Цель настоящего обзора состояла в том, чтобы представить роль физических упражнений и их влияние на ВЗК. В этой связи ведётся поиск дополнительных инструментов для повышения частоты достижения и удержания ремиссии. В последнее время получены данные, что физическая нагрузка индуцирует каскад противовоспалительных цитокинов, специфически запускаемый за счет экспоненциального увеличения мышечного интерлейкин 6, и при регулярных тренировках в период ремиссии может снизить базальные уровни циркулирующих воспалительных маркеров и потенциально уменьшить хроническое воспаление при ВЗК. Рекомендации врача по физической активности в период ремиссии могут быть эффективны в качестве дополнительного компонента противорецидивного лечения.
Об авторах
С. В. КостюкевичРоссия
Костюкевич Сергей Владимирович — доктор медицинских наук, заведующий кафедрой медицинской биологии
ул. Кирочная, д.41, г. Санкт-Петербург, 191015
И. Г. Бакулин
Россия
Бакулин Игорь Геннадьевич — профессор, доктор медицинских наук, декан лечебного факультета, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С.М. Рысса
ул. Кирочная, д.41, г. Санкт-Петербург, 191015
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Рецензия
Для цитирования:
Костюкевич С.В., Бакулин И.Г. Физические упражнения как эффективная адъювантная терапия при ремиссии воспалительных заболеваний кишечника (обзор литературы). Колопроктология. 2024;23(1):152-161. https://doi.org/10.33878/2073-7556-2024-23-1-152-161
For citation:
Kostyukevich S.V., Bakulin I.G. Physical exercises as an effective adjuvant therapy of IBD in remission (review). Koloproktologia. 2024;23(1):152-161. https://doi.org/10.33878/2073-7556-2024-23-1-152-161