THE ROLE OF ANTIBIOTIC PROPHYLAXIS IN PREVENTION OF INTESTINAL STOMAS CLOSURE
https://doi.org/10.33878/2073-7556-2016-0-2-25-31
Abstract
AIM. To evaluate the effectiveness of antibiotic prophylaxis in closure of preventive intestinal stomas. MATERIALS AND METHODS. In a main (I-first) group included 99 patients who did not undergo antibiotic prophylaxis (ABP). In the control (II-second) group were 96 patients who underwent ABP by a single intravenous injection of 1,2 g of amoxycillin / clavulanic acid in 30 minutes before the operation. RESULTS. The overall incidence of complications in the main and control groups was 23 (23,3 %) and 27 (27,9 %), respectively (p=0,53). Among them, the surgical site infection (SSI) was the first place in the frequency of complications: in group I in 12 (12,2 %) in group II in 11 (11,4 %) patients (p=0,35 ). Postoperative diarrhea with frequency of stools 5 or more times per day in second place infrequency, but has evolved into two less in the main than in the control group - in 4 (4,0 %), and 8 (8.3 %) patients, respectively (p=0,212). Febrile fever was detected more frequently in the first group than in the second - 6 (6,1 %) and 1 (1,0 %) cases, respectively (p=0,06). Other complications were the paresis of gastrointestinal tract (p=0,76), bleeding from the formed anastomosis area (p=0,149), pneumothorax (p=0,324), cystitis (p=0,309) and lobar pneumonia (p=0,309). There were no statistically significant complications associated with one of two groups. CONCLUSION. The results of the study not prove the effectiveness of the ABP in patients undergoing closure preventive intestinal stoma. This does not allow us to recommend its routine use. The question of prophylactic antibiotics should be taken individually, considering all the possible risks.
About the Authors
Y. A. Shelygin
State Scientific Centre of Coloproctology; Russian Medical Postgraduate Education Academy
Russian Federation
Russian Federation
S. I. Achkasov
State Scientific Centre of Coloproctology
Russian Federation
Russian Federation
D. V. Piliev
State Scientific Centre of Coloproctology
Russian Federation
Russian Federation
O. I. Sushkov
State Scientific Centre of Coloproctology
Russian Federation
Russian Federation
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For citations:
Shelygin Y.A., Achkasov S.I., Piliev D.V., Sushkov O.I. THE ROLE OF ANTIBIOTIC PROPHYLAXIS IN PREVENTION OF INTESTINAL STOMAS CLOSURE. Koloproktologia. 2016;(2):25-31. (In Russ.) https://doi.org/10.33878/2073-7556-2016-0-2-25-31
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