Quality of life after rectal cancer surgery (systematic review)
https://doi.org/10.33878/2073-7556-2021-20-1-59-67
Abstract
Aim: search for modifiable and unmodifiable risk factors affecting the quality of life of patients after rectal cancer surgery.
Materials and methods: the literature search was done according to the keywords: quality of life, rectal cancer, low anterior resection syndrome. Twelve prospective randomized studies, 2 cohort studies, and 2 meta-analyses are included in the study. The quality of life was assessed in the analyzed studies by using questionnaires for cancer patients and updated questionnaires for colorectal cancer: EORTC QLQ-CR29, QLQ-C30, QLQ-CR38, BIQ.
Results: the literary data on influence of gender, age, surgery, stoma, and chemoradiotherapy on life quality of patients after rectal cancer surgery was analyzed.
Conclusion: the most significant factor affecting the life quality of patients with rectal cancer is a violation of the body image if it is necessary to form the stoma on the anterior abdominal wall. The manifestations of the low anterior resection syndrome and the urination problems are significant risk factors in the case of restoration of bowel continuity.
About the Authors
A. B. Serebriy
Ryzhikh National Medical Research Center of Coloproctology
Russian Federation
Russian Federation
Alyona B. Serebriy
Salyama Adilya str., 2, Moscow, 123423
E. A. Khomyakov
Ryzhikh National Medical Research Center of Coloproctology;
Russian Medical Academy of Continuous Professional Education of Health Ministry of Russia
Evgeniy A. Khomyakov
Salyama Adilya str., 2, Moscow, 123423,
Barrikadnaya str., 2/1-1, Moscow, 125993
I. O. Nafedzov
Ryzhikh National Medical Research Center of Coloproctology
Islam O. Nafedzov
Salyama Adilya str., 2, Moscow, 123423
O. Yu. Fomenko
Ryzhikh National Medical Research Center of Coloproctology
Oksana Yu. Fomenko
Salyama Adilya str., 2, Moscow, 123423
E. G. Rybakov
Ryzhikh National Medical Research Center of Coloproctology
Evgeny G. Rybakov
Salyama Adilya str., 2, Moscow, 123423
References
1. WHO Quality of Life Assessment Group. What quality of life? World Health Forum. 1996;17(4):354-356.
2. Ibrahim K, Priambodo AP, Nur’aeni A et al. Quality of life and characteristics of colostomy patients. Journal of Coloproctology (JCOL). 2017;12:239-246. DOI: 10.1016/j.jcol.2018.06.001
3. Rybakov E.G., Nafedzov I.O., Khomyakov E.A. et al. Methods of conservative treatment of lowanterior resection syndrome (review). Koloproktologia. 2018; no. 3, pp. 79-83. (In Russ.) DOI: 10.33878/2073-7556-2018-0-3-79-83
4. Bryant CL, Lunniss PJ, Knowles CH et al. Anterior resection syndrome. Lancet Oncol. 2012;13(9):403-408. DOI: 10.1016/S1470-2045(12)70236-X
5. Lee CM, Huh JW, Park YA et al. Risk factors of permanent stomas in patients with rectal cancer after low anterior resection with temporary stomas. Yonsei Med J. 2015;56(2):447-453. DOI: 10.3349/ymj.2015.56.2.447
6. Maisey NR, Norman A, Watson M et al. Baseline quality of life predicts survival in patients with advanced colorectal cancer. Eur J Cancer. 2002;13(10):1351-1357. DOI: 10.1016/s0959-8049(02)00098-9
7. Braun DP, Gupta D, Grutsch JF et al. Can changes in health related quality of life scores predict survival in stages III and IV colorectal cancer? Health and quality of life outcomes. 2011;13:62. DOI: 10.1186/1477-7525-9-62
8. Sprangers MA, Cull A, Bjordal K et al. The European Organization for Research and Treatment of Cancer approach to developing questionnaire modules: an update and overview. Qual Life Res. 1993;2(4):287-295. DOI: 10.1007/BF00434800
9. Sprangers MA, te Velde A, Aaronson NK. The construction and testing of the EORTC colorectal cancer-specific quality of life questionnaire module (QLQ-CR38). European Organization for Research and Treatment of Cancer Study Group on Quality of Life. Eur J Cancer. 1999;35(2):238-247. DOI: 10.1016/s0959-8049(98)00357-8
10. Gujral S, Conroy T, Fleissner C et al. European Organisation for Research and Treatment of Cancer Quality of Life Group Assessing quality of life in patients with colorectal cancer: an update of the EORTC quality of life questionnaire. European Journal of Cancer. 2007;43:1564-1573. DOI: 10.1016/j.ejca.2007.04.005
11. Khozhaev A.A. EORTC qlq-cr29 questionnaire (colorectal cancer): language, cultural adaptation and validation. KazNMU bulletin. 2016; no. 1, pp. 691-693. (In Russ.).
12. Veltcamp Helbach M, Koedam TWA, Knol JJ et al. Quality of life after rectal cancer surgery: differences between laparoscopic and transanal total mesorectal excision. Surg Endosc. 2019;33(1):79-87. DOI: 10.1007/s00464-018-6276-z
13. Schmidt CE, Bestmann B, Küchler T et al. Gender differences in quality of life of patients with rectal cancer. A five-year prospective study. World J Surg. 2005;29(12):1630-1641. DOI: 10.1007/s00268-005-0067-0
14. Pérez Lara FJ, Navarro Piñero A, de la Fuente Perucho A. Study of factors related to quality of life in patients with locally advanced rectal cancer. Rev Esp Enferm Dig. 2004;96(11):746-757. DOI: 10.4321/s1130-01082004001100002
15. Kinoshita Y, Izukura R, Miyazono M et al. Effect of age factors on health-related quality of life in patients with lower rectal cancer after sphincter-saving surgery: A 1-year longitudinal study. Arch Gerontol Geriatr. 2018;79:185-191. DOI: 10.1016/j.archger.2018.09.004
16. Li K, Li JP, Huang MJ et al. Quality of life of elderly Chinese rectal cancer patients after preventative anal surgery: a cohort study. Hepatogastroenterology. 2013;60(126):1376-1382
17. Haviland J, Sodergren S, Calman L et al. Social support following diagnosis and treatment for colorectal cancer and associations with health-related quality of life: Results from the UK ColoREctal Wellbeing (CREW) cohort study. Psychooncology. 2017;26(12):2276- 2284. DOI: 10.1002/pon.4556
18. Grimmett C, Bridgewater J, Steptoe A et al. Lifestyle and quality of life in colorectal cancer survivors. Quality of Life Research. 2011;20(8):1237-1245. DOI: 10.1007/s11136-011-9855-1
19. Engel J, Kerr J, Schlesinger-Raab A et al. Quality of life in rectal cancer patients: a four-year prospective study. Annals of surgery. 2003;238(2):203-213. DOI: 10.1097/01.sla.0000080823.38569.b0
20. Feddern ML, Emmertsen KJ, Laurberg S Quality of life with or without sphincter preservation for rectal cancer. Colorectal Dis. 2019;21:1051-1057. DOI: 10.1111/codi.14684
21. Trenti L, Galvez A, Biondo S et al. Quality of life and anterior resection syndrome after surgery for mid to low rectal cancer: A cross-sectional study. European Journal of Surgical Oncology. 2018;44(7):1031-1039. DOI: 10.1016/j.ejso.2018.03.025
22. van der Heijden JAG, Thomas G, Caers F et al. What you should know about the low anterior resection syndrome-Clinical recommendations from a patient perspective. Eur J Surg Oncol. 2018;44:1331- 1337. DOI: 10.1016/j.ejso.2018.05.010
23. Veldkamp R, Kuhry E, Hop WC et al. Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol. 2005;6:477-84. DOI: 10.1016/S1470-2045(05)70221-7
24. Karachun A.M., Petrova E.A., Sinenchenko G.I. et al. Comparative analysis of quality of life after laparoscopic and open procedures for upper and middle rectal cancer. Colorectal Oncology. 2018; no. 8(1); pp. 28-33. (In Russ.). DOI: 10.17650/2220-3478-2018-8-1-28-33
25. Andersson J, Angenete E, Gellerstedt M et al. Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial. Br J Surg. 2016;103(12):1746. DOI: 10.1002/bjs.10280
26. Hirpara DH, Azin A, Mulcahy V et al. The impact of surgical modality on self-reported body image, quality of life and survivorship after anterior resection for colorectal cancer – a mixed methods study. Can J Surg. 2019;62(4):235-242. DOI: 10.1503/cjs.014717
27. Schwartz CE, Sprangers MA. Methodological approaches for assessing response shift in longitudinal health-related quality-of-life research. Soc Sci Med. 1999;48(11):1531-48. DOI: 10.1016/s0277-9536(99)00047-7
28. Sprangers MA, Schwartz CE Integrating response shift into healthrelated quality of life research: a theoretical model. Soc Sci Med. 1999;13(11):1507-1515. DOI: 10.1016/s0277-9536(99)00045-3
29. Wrenn SM, Cepeda-Benito A, Ramos-Valadez DI et al. Patient Perceptions and Quality of Life After Colon and Rectal Surgery: What Do Patients Really Want? Dis Colon Rectum. 2018;61(8):971-978. DOI: 10.1097/DCR.0000000000001078
30. Wang L, Wang X, Lo A et al. Effects of radiation and surgery on function and quality of life (QOL) in rectal cancer patients. Am J Surg. 2018;215(5):863-866. DOI: 10.1016/j.amjsurg.2018.01.014
31. Morielli AR, Usmani N, Boulé NG et al. Exercise during and after neoadjuvant rectal cancer treatment (the EXERT trial): study protocol for a randomized controlled trial. Trials. 2018;19(1):35. DOI: 10.1186/s13063-017-2398-1
32. Loos M, Quentmeier P, Schuster T et al. Effect of Preoperative Radio(chemo)therapy on Long-term Functional Outcome in Rectal Cancer Patients: A Systematic Review and Meta-analysis. Annals of Surgical Oncology. 2012;20(6):1816-1828. DOI: 10.1245/s10434-012-2827-z
33. van der Valk MJM, Marijnen CAM, van Etten B, et al. Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer – Results of the international randomized RAPIDO-trial. Radiother Oncol. 2020; Jun 147:75-83. DOI: 10.1016/j.radonc.2020.03.011
Review
For citations:
Serebriy A.B., Khomyakov E.A., Nafedzov I.O., Fomenko O.Yu., Rybakov E.G. Quality of life after rectal cancer surgery (systematic review). Koloproktologia. 2021;20(1):59-67. https://doi.org/10.33878/2073-7556-2021-20-1-59-67
Views:
982
Email this article 
