THE FIRST EXPERIENCE OF CONTRAST-ENHANCED ULTRASOUND IN EPITHELIAL RECTAL TUMORS
https://doi.org/10.33878/2073-7556-2020-19-4-57-70
Abstract
AIM: to evaluate the diagnostic capabilities of contrast-enhanced ultrasound for the diagnostics of epithelial rectal tumors.
PATIENTS AND METHODS: the study included 15 patients, who underwent endorectal ultrasound and transvaginal contrast-enhanced ultrasound. All the patients underwent surgery.
RESULTS: morphology revealed adenomas in 9 cases, and adenocarcinomas with different invasion depth in 6 cases. When analyzing the tumors contrast, significant differences in arrival time of contrasting between adenomas and adenocarcinomas were obtained (p = 0.041), and the contrast enhancement of adenocarcinomas was faster (p = 0.036). Negative correlations of peak intensity of contrast enhancement of hypoenhanced zones in adenocarcinoma with indices T (rxy =-0.781; p = 0.001) and N (rxy = - 0.519; p = 0.047)and a positive correlation with the tumor differentiation degree (rxy=0.742; p = 0.002) were established. Also, the negative correlation of the arrival time with the index T (rxy=-0.552; p=0.033) was found.
CONCLUSION: contrast-enhanced ultrasound is an imaging technique that allows real-time qualitative and quantitative assessment of tumor tissue perfusion. The method is not standardized, but it can be a useful non-invasive method for assessing the blood supply of rectal tumors at the preoperative stage, and also has the potential to assess risk factors for lymphogenic metastasis.
About the Authors
E. M. Bogdanova
Ryzhikh National Medical Research Center of Coloproctology
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
L. P. Orlova
Ryzhikh National Medical Research Center of Coloproctology
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
Yu. L. Trubacheva
Ryzhikh National Medical Research Center of Coloproctology
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
E. A. Khomyakov
Ryzhikh National Medical Research Center of Coloproctology
Salyama Adilya str., 2, Moscow, 123423, Russia
Salyama Adilya str., 2, Moscow, 123423, Russia
E. G. Rybakov
Ryzhikh National Medical Research Center of Coloproctology
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
Russian Federation
Salyama Adilya str., 2, Moscow, 123423, Russia
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Review
For citations:
Bogdanova E.M., Orlova L.P., Trubacheva Yu.L., Khomyakov E.A., Rybakov E.G. THE FIRST EXPERIENCE OF CONTRAST-ENHANCED ULTRASOUND IN EPITHELIAL RECTAL TUMORS. Koloproktologia. 2020;19(4):57-70. https://doi.org/10.33878/2073-7556-2020-19-4-57-70
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