ACUTE SEVERE ULCERATIVE COLITIS (case report)
https://doi.org/10.33878/2073-7556-2019-18-4-130-133
Abstract
The case report of the onset of acute severe ulcerative colitis (ASUC) in a young, previously healthy patient. The UC was revealed department of the infectious disease in general hospital, a proper conservative treatment was started but was ineffective. The patient was taken to the colorectal surgery unit of the tertiary referral center. His status was very poor including metabolic changes and dehydration, anemia, thrombocytopenia, systemic inflammatory response syndrome. Despite intensive therapy, the condition impaired and massive intestinal bleeding recurred. Urgent colproctectomy with end ileostomy was performed. Pathomorphological study verified the diagnosis of ulcerative colitis – highly active inflammation involving the submucosal and muscular layers of the intestine with multiple crypt abscesses. The patient was discharged 2 days after surgery. Follow-up was 3.5 years, patient in good condition without restrictions.
About the Authors
V. E. PakRussian Federation
Irkutsk
N. S. Korotaeva
Irkutsk
E. Yu. Chashkova
Irkutsk
A. A. Zheltovskaya
Irkutsk
I. E. Makeeva
Irkutsk
References
1. Ivashkin V.T., Shelygin Yu.A., Khalif I.L. еt al. Clinical guide of Russian association of gastroenterology and Russian association of coloproctology on diagnostics and treatment of ulcerative colitis. Koloproktologia. 2017; no. 1(59), pp. 6-30. (in Russ.).
2. Chen JH, Andrews JM, Kariyawasam VC. et al. Review article: acute severe ulcerative colitis – evidence-based consensus statements. Aliment Pharmacol Ther. 2016;44(2):127-144. doi: 10.1111/apt.13670
3. Dulai PS, Jairath V. Acute severe ulcerative colitis: latest evidence and therapeutic implications. Ther Adv Chronic Dis. 2017;9(2):65-72. doi: 10.1177/2040622317742095
4. Hindryckx P, Jairath V, D’Haens G. Acute severe ulcerative colitis: from pathophysiology to clinical management. Nat Rev Gastroenterol Hepatol. 2016; 13(11): 654-664. doi: 10.1038/nrgastro.2016.116
5. Randall J, Singh B, Warren BF. et al. Delayed surgery for acute severe colitis is associated with increased risk of postoperative complications. Br J Surg. 2010;97(3):404-409. doi: 10.1002/bjs.6874
6. Seah D, De Cruz P. Review article: the practical management of acute severe ulcerative colitis. Aliment Pharmacol Ther. 2016; 43(4):482-513. doi: 10.1111/apt.13491
Review
For citations:
Pak V.E., Korotaeva N.S., Chashkova E.Yu., Zheltovskaya A.A., Makeeva I.E. ACUTE SEVERE ULCERATIVE COLITIS (case report). Koloproktologia. 2019;18(4):130-133. (In Russ.) https://doi.org/10.33878/2073-7556-2019-18-4-130-133