Болезнь Крона червеобразного отростка. Обзор литературы с описанием отдаленного результата хирургического лечения через 37 лет

ЦЕЛЬ: на основании анализа собственного клинического наблюдения и литературного обзора рассмотреть проблему лечения болезни Крона червеобразного отростка.

ПАЦИЕНТЫ И МЕТОДЫ: приводится отдаленный результат (37 лет) пациентки, перенесшей в возрасте 28 лет правостороннюю гемиколэктомию по поводу болезни Крона червеобразного отростка. В течение указанных лет она не получала лечения по поводу данного заболевания. В 2024 году проведено комплексное клинико-инструментальное, молекулярно-генетическое исследование.

РЕЗУЛЬТАТЫ: по результатам обследования, данных за рецидив болезни Крона не выявлено, однако при молекулярно-генетическом исследовании выявлены 2 клинически значимых генотипа, связанных с риском развития болезни Крона. Представлен обзор отечественной и иностранной литературы, включая роли брыжейки кишечника в патогенезе болезни Крона.

ЗАКЛЮЧЕНИЕ: при изолированной форме болезни Крона червеобразного отростка аппендэктомия является приемлемым вариантом хирургического лечения; при поражении основания червеобразного отростка с вовлечением купола слепой кишки следует рассмотреть варианты резекции ободочной кишки.

Хирургические вмешательства приводят к выздоровлению/длительной ремиссии.

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