Crohn's disease of the appendix. Late outcome of surgery after 37 years (clinical case and review)
V. M. Timerbulatov,
Sh. V. Timerbulatov,
L. R. Aitova,
D. V. Lopatin,
A. R. Gafarova,
R. R. Akhmerov,
I. D. Gayazov https://doi.org/10.33878/2073-7556-2025-24-3-201-208
Abstract
OBJECTIVE: based on the analysis of our own clinical observation and literature review, to consider the problem of treatment of Crohn's disease of the appendix.
PATIENT AND METHODS: the long-term result (37 years old) of a patient who underwent right-sided hemicolectomy for Crohn's disease of the appendix at the age of 28 is presented. During these years, she did not receive treatment for this disease. In 2024, a comprehensive clinical, instrumental, and molecular genetic study was conducted.
RESULTS: According to the results of the examination, no data were found for the recurrence of Crohn's disease, however, a molecular genetic study revealed 2 clinically significant genotypes associated with the risk of Crohn's disease. A review of domestic and foreign literature is presented, including the role of the intestinal mesentery in the pathogenesis of Crohn's disease.
CONCLUSION: in the isolated form of Crohn's disease of the appendix, appendectomy is an acceptable surgical treatment option; if the base of the appendix is affected and the cecum dome is involved, colon resection options should be considered. Surgical interventions lead to recovery/long-term remission.
About the Authors
V. M. Timerbulatov
Bashkir State Medical University
Russian Federation
Russian Federation
Vil M. Timerbulatov.
Lenina st., 3, Ufa, 450008
Sh. V. Timerbulatov
Bashkir State Medical University
Russian Federation
Russian Federation
Shamil V. Timerbulatov.
Lenina st., 3, Ufa, 450008
L. R. Aitova
Bashkir State Medical University
Russian Federation
Russian Federation
Liliya R. Aitova.
Lenina st., 3, Ufa, 450008
D. V. Lopatin
Bashkir State Medical University
Russian Federation
Russian Federation
Denis V. Lopatin.
Lenina st., 3, Ufa, 450008
A. R. Gafarova
Bashkir State Medical University
Russian Federation
Russian Federation
Aigul R. Gafarova.
Lenina st., 3, Ufa, 450008
tel.: +7 (937) 303-58-88
R. R. Akhmerov
Clinical Hospital of Emergency Medical Care
Russian Federation
Russian Federation
Ruslan R. Akhmerov.
Batyrskaya st., 39/2, Ufa, 450106
I. D. Gayazov
Clinical Hospital of Emergency Medical Care
Russian Federation
Russian Federation
Ilmir D. Gayazov.
Batyrskaya st., 39/2, Ufa, 450106
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Timerbulatov V.M., Timerbulatov Sh.V., Aitova L.R., Lopatin D.V., Gafarova A.R., Akhmerov R.R., Gayazov I.D. Crohn's disease of the appendix. Late outcome of surgery after 37 years (clinical case and review). Koloproktologia. 2025;24(3):201-208. (In Russ.) https://doi.org/10.33878/2073-7556-2025-24-3-201-208
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