CLINICAL GUIDELINES. Perianal abscess (K61, K61.0, K61.1, K61.2, K61.3, K61.4), adults, children

1. Shelygin Yu.A., Blagodarny L.A. Handbook of coloproctology. M.: Publishing house “Litterra”. 2012; с. 96-114. (in Russ.).

2. Gosselink MP, Onkelen RS, Schouten WR. The cryptoglandular theory revisited. Colorectal Dis. 2015;17:1041–1043.

3. Sugrue J, Nordenstam J, Abcarian H. Pathogenesis and persistence of cryptoglandular anal fistula: a systematic review. Tech Coloproctol. 2017;21(6):425–432.

4. Ladinsky A, Smiley A, Latifi R. Elderly Patients Managed NonOperatively with Abscesses of the Anorectal Region Have Five Times Higher Rate of Mortality Compared to Non-Elderly. Int J Environ Res Public Health. 2023;20(7):5387.

5. Guner Ozenen G, Akaslan Kara A, Ozer A, et al. Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics. Pediatr Surg Int. 2023;39(1):272.

6. Shcherbakova O.V. Primary immunodeficiency conditions simulating inflammatory bowel diseases: clinical aspects and problems of differential diagnosis. The Almanac of Clinical Medicine. 2023;51(8):456– 468. (in Russ.).

7. Gosemann J-H, Lacher M. Perianal abscesses and fistulas in infants and children. Eur J Pediatr Surg. 2020;30(5):386–390.

8. Ding W, Sun Y-R, Wu Z-j. Treatment of perianal abscess and fistula in infants and young children: from basic etiology to clinical features. Am Surg. 2021;87(6):927–932.

9. Newton K, Dumville J, Briggs M, et al. PPAC2 Collaborators. Postoperative Packing of Perianal Abscess Cavities (PPAC2): randomized clinical trial. Br J Surg. 2022;109(10):951–957.

10. Pearce L, Newton K, Smith SR, et al. North West Research Collaborative. Multicentre observational study of outcomes after drainage of acute perianal abscess. Br J Surg. 2016;103(8):1063– 1068.

11. Bolkvadze E.E., et al. Complex forms of acute paraproctitis. Literature review. Koloproktologia. 2009;27(1):38–46. (in Russ.).

12. Sahnan K, Askari A, Adegbola SO, et al. Natural history of anorectal sepsis. Br J Surg. 2017;104(13):1857–1865.

13. Adamo K, Sandblom G, Brännström F, et al. Prevalence and recurrence rate of perianal abscess-a population-based study, Sweden 1997-2009. Int J Colorectal. 2016;31(3):669–673.

14. Geraskin A.V., Dronov A.F., Smirnov A.N. Pediatric coloproctology: A guide for doctors. M.: «Content». 2012; 664 p. (in Russ.).

15. Zyuzko D.D., Shcherbakova O.V. Acute paraproctitis and pararectal fistulas in children. Literature review. Russian Bulletin of Pediatric Surgery, Anesthesiology and Intensive Care. 2023;13(3):419–430. (in Russ.).

16. Razumovsky A.Y. Pediatric surgery: National guidelines (edited by A.Y. Razumovsky. — 2nd ed., reprint. and an addendum). M.: GEOTAR-Media. 2021;280 p. (in Russ.).

17. Kuzmin A.I., Munin A.G., Barskaya M.A., et al. Features of diagnosis and treatment of paraproctitis in children. Pediatric surgery. 2020;24(1):29–34. (in Russ.).

18. Sigmon DF, Emmanuel B, Tuma F. Perianal Abscess. StatPearls [Internet] Treasure Island (FL): StatPearls Publishing. 2024; Available from: https://www.ncbi.nlm.nih.gov/books/NBK459167/

19. Akinmoladun O, Hatch QM. Anal Cryptoglandular Suppuration: Evidence-Based Management. Surg Clin North Am. 2024;104(3):491– 501.

20. Gaertner WB, Burgess PL, Davids JS, et al. On behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons. The American Society of Colon and Rectal Surgeons. Clinical Practice Guidelines for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula. Diseases of the Colon & Rectum. 2022;65(8):964–985.

21. Tan Tanny SP, Wijekoon N, Nataraja RM, et al. Surgical management of perianal abscess in neonates and infants. ANZ J Surg. 2020;90(6):1034–1036.

22. Hwang JY, Yoon HK, et al. Transperineal ultrasonography for evaluation of the perianal fistula and abscess in pediatric Crohn disease: preliminary study. Ultrasonography. 2014;33(3):184–190.

23. Crowley E, Ma C, Guizzetti L, et al. Recommendations for Standardizing MRI-based Evaluation of Perianal Fistulizing Disease Activity in Pediatric Crohn’s Disease Clinical Trials. Inflamm Bowel Dis. 2024;30(3):357–369.

24. Maconi G, Greco MT, Asthana AK. Transperineal ultrasound for perianal fistulas and abscesses — a systematic review and metaanalysis. Ultraschall Med. 2017;38(3):265–272.

25. Kumar S, Chaudhary RK, Shah SS, et al. Current update on the role of endoanal ultrasound: a primer for radiologists. Abdom Radiol (NY). 2024; Published online.

26. Amato A, Bottini C, De Nardi P, et al. Evaluation and management of perianal abscess and anal fistula: SICCR position statement. Tech Coloproctol. 2020;24:127–143.

27. Nuernberg D, Saftoiu A, Barreiros AP, et al. EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound. Ultrasound Int Open. 2019;5(1):34–51.

28. Ding YW, Yin HQ, Liang HT, et al. Can transcutaneous perianal ultrasonography be the first-line diagnostic instrument for evaluating pediatric perianal fistulas? Gastroenterol Rep (Oxf). 2022;10:goac071.

29. Zinicola R, Cracco N, Rossi G, et al. Acute supralevator abscess: the little we know. Ann R Coll Surg Engl. 2022;104(9):645–649.

30. Tabari A, Kaplan JL, Huh SY, et al. Clinical characteristics and MRI-based phenotypes of perianal abscess formation in children with fistulizing Crohn’s Disease. Front Pediatr. 2022;10:1045583.

31. Toyonaga T, Matsushima M, Tanaka Y, et al. Microbiological analysis and endoanal ultrasonography for diagnosis of anal fistula in acute anorectal sepsis. Int J Color Dis. 2007;22:209–213.

32. Du J, Miao Y, Zhen S, et al. No Difference in the Pathogenic Microorganisms Among Different Types of Anorectal Abscesses: A Retrospective Study. Cureus. 2024;16(3):e. 56504.

33. Vogel JD, Johnson EK, Morris AM, et al. Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula. Dis Colon Rectum. 2016;59(12):1117–1133.

34. Ommer A, Herold A, Berg E, et al. German S3 guidelines: anal abscess and fistula (second revised version). Langenbecks Arch Surg. 2017;402(2):191–201.

35. Yamana T. Japanese Practice Guidelines for Anal Disorders II. Anal fistula. J Anus Rectum Colon. 2018;2(3):103–109.

36. Steele SR, Kumar R, Feingold DL, et al. Standards Practice Task Force of the American Society of Colon and Rectal Surgeons. Practice parameters for the management of perianal abscess and fistula-inano. Dis Colon Rectum. 2011;54(12):1465–1474.

37. Pearce L, Newton K, Smith SR, et al. Multicentre observational study of outcomes after drainage of acute perianal abscess. Br J Surg. 2016;103(8):1063–1068.

38. Abcarian H. Anorectal Infection: Abscess-Fistula. Clin Colon Rectal Surg. 2011;24(1):14–21.

39. Shi Y, Zhi C, Cheng Y, et al.A systematic review and meta-analysis of incision and seton drainage in the treatment of high perianal abscess. Ann Palliat Med. 2021;10(9):9830–9840.

40. Juth Karlsson A, Salö M, Stenström P. Outcomes of Various Interventions for First-Time Perianal Abscesses in Children. Biomed Res Int. 2016; 9712854.

41. Gong Z, Han M, Wu Y, et al. Treatment of First-Time Perianal Abscess in Childhood, Balance Recurrence and Fistula Formation Rate with Medical Intervention. Eur J Pediatr Surg. 2018;28(4):373–377.

42. Yin W, Li Y, Zhang J, et al. Natural course of perianal abscess in infants: a real-world study. Sci Rep. 2023;13(1):18416.

43. Christison-Lagay ER, Hall JF, Wales PW, et al. Nonoperative management of perianal abscess in infants is associated with decreased risk for fistula formation. Pediatrics. 2007;120(3):e548–52.

44. Kang C, Liu G, Zhang R, et al. Intermediate-term evaluation of initial non-surgical management of pediatric perianal abscess and fistula-in-ano. Surg Infect (Larchmt). 2022;5(23):465–469.

45. Stokes R, Wanaguru D, Saadi A, et al. Management of perianal abscesses in infants without general anaesthesia: a systematic review of the literature. Pediatr Surg Int. 2020;36(11):1317–1325.

46. Sözener U, Gedik E, Kessaf AA, et al. Does adjuvant antibiotic treatment after drainage of anorectal abscess prevent development of anal fistulas? Dis Colon rectum. 2011;54:923–929.

47. He J, Ni Z, Li Z. Efficacy of surgical treatment of perianal infection in patients with hematological malignancy. Medicine (Baltimore). 2024;103(19):e38082.

48. Mocanu V, Dang JT, Ladak F, et al. Antibiotic use in prevention of anal fistulas following incision and drainage of anorectal abscesses: A systematic review and meta-analysis. Am J Surg. 2019;217(5):910–917.

49. Afşarlar Ç, Karaman A, Tanır G, et al. Perianal abscess and fistula-in-ano in children: clinical characteristic, management and outcome. Pediatr Surg Int. 2011;10:1063–1068.

50. Chakarov D, Hadzhieva E, Kalchev Y, et al. Aerobic Microbiological Spectrum and Antibiotic Resistance in Children Operated for Anorectal Abscesses. J Clin Med. 2024;13(8):2414.

51. Smith SR, Newton K, Smith JA, et al. Internal dressings for healing perianal abscess cavities. Cochrane Database Syst Rev. 2016;26(8).

52. Malik AI, Nelson RL, Tou S. Incision and drainage of perianal abscess with or without treatment of anal fistula. Cochrane Database of Systematic Reviews. 2010; Issue 7: Art. No.: CD006827.

53. Galanis I, Chatzimavroudis G, Christopoulos P, et al. Prospective Randomized Trial of Simple Drainage vs. Drainage and Initial Fistula Management for Perianal Abscesses. J Gastrointest Dig Syst. 2016;6:382.

54. Ding C, Chen Y, Yan J, et al. Risk factors for therapy failure after incision and drainage alone for perianal abscesses in children. Front Pediatr. 2024;8(12):1342892.

55. Bałaż K, Trypens A, Polnik D, et al. Perianal abscess and fistulain-ano in children — evaluation of treatment efficacy. Is it possible to avoid recurrence? Pol Przegl Chir. 2020;92(2):29–33.

56. Sun Y, Hao S, Zhang X, et al. A Systematic Review and MetaAnalysis of Comparing Drainage Alone versus Drainage with Primary Fistula Treatment for the Perianal Abscess in Children. Eur J Pediatr Surg. 2024;34(3):204–214.

57. Badgwell BD, Chang GJ, Rodriguez-Bigas MA, et al. Management and outcomes of anorectal infection in the cancer patient. Ann Surg Oncol. 2009;16:2752–2758.

58. Büyükaşik Y, Ozcebe OI, Sayinalp N, et al. Perianal infections in patients with leukemia: importance of the course of neutrophil count. Dis Colon Rectum. 1998;41:81–85.

59. Shtyrkova S.V., Klyasova G.A., Danishyan K.I., et al. Perinatal infection in patients with hemoblastosis: risk factors and prevention possibilities. Therapeutic Archive. 2016;7:72–77. (in Russ.).

60. Morcos B, Amarin R, Abu Sba A, et al. Contemporary management of perianal conditions in febrile neutropenic patients. Eur J Surg Oncol. 2013;39(4):404–407.

61. Solmaz S, Korur A, Gereklioğlu Ç, et al. Anorectal Complications During Neutropenic Period in Patients with Hematologic Diseases. Mediterr J Hematol Infect Dis. 2016;8(1):e2016019.

62. Shtyrkova S.V., Soboleva O.A., Sabirov K.R., et al. Diagnosis and treatment of complex forms of acute paraproctitis in patients with tumor diseases of the blood system. Koloproktologia. 2024;23(1):117–128. doi: 10.33878/2073-7556-2024-23-1-117-128 (in Russ.).

63. Renzi S, Bartram J, Ali S, et al. Perianal Infections in Children With Acute Myeloid Leukemia: A Report From the Canadian Infection in Acute Myeloid Leukemia Research Group. J Pediatric Infect Dis Soc. 2019;8(4):354–357.