Granular cell tumor of the perineum (clinical case)
https://doi.org/10.33878/2073-7556-2023-22-4-121-126
Abstract
Aim: to present a clinical case of a rare granular cell tumor (Abrikosov’s tumor) with perianal site.
Patients and Methods: a patient had a slowly progressive growth of a perianal tumor. The tumor with dimensions of 40 × 30 mm intimately adheres to the lower ampullary rectum and anterior portion of m. levator ani, no signs of malignant transformation occurred. Trepanobiopsy was performed followed by immunohistochemical study. The biopsies contain mainly fibrous tissue and clusters of cells with rounded nuclei and granular cytoplasm. Immunohistochemistry showed diffuse positive cytoplasmic reaction with antibodies to S100. The tumor was positive for CD8, vimentin and negative for GFAP. The expression of the Ki67 protein was 2%. Diagnosis: granulocellular tumor (Abrikosov’s tumor), the tumor was removed by perineal access.
Resultss: the removal of the tumor, originating from the low rectum, was performed with perineal access and with the restoration of the muscular layer of the bowel wall. No complications occurred, patient discharged 5 days after surgery.
Conclusion: Abrikosov’s tumor is a rare benign neoplasm. Surgery is possible in coloproctological units with sufficient level of surgeons.
About the Authors
R. R. Shakirov
Republican Clinical Hospital;
Kazan State Medical University;
Republican Clinical Oncological Dispensary of the Ministry of Health of the Republic of Tatarstan named after
Professor M.Z. Sigal
Russian Federation
Russian Federation
Rais R. Shakirov, Orenburg tract, 138, Kazan, 420064;
Butlerova st., 49, Kazan, 420012;
Sibirskiy trakt st., 29, Kazan, 420029
O. Yu. Karpukhin
Republican Clinical Hospital;
Kazan State Medical University
Russian Federation
Russian Federation
Oleg Yu. Karpukhin, Orenburg tract, 138, Kazan, 420064;
Butlerova st., 49, Kazan, 420012
M. I. Ziganshin
Republican Clinical Hospital
Russian Federation
Russian Federation
Marat I. Ziganshin,
Orenburg tract, 138, Kazan, 420064
I. S. Raginov
Republican Clinical Hospital;
Kazan (Volga Region) Federal University
Russian Federation
Russian Federation
Ivan S. Raginov, Orenburg tract, 138, Kazan, 420064;
Kremlevskaya st., 18, bld. 1, Kazan, 420008
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Review
For citations:
Shakirov R.R., Karpukhin O.Yu., Ziganshin M.I., Raginov I.S. Granular cell tumor of the perineum (clinical case). Koloproktologia. 2023;22(4):121-126. https://doi.org/10.33878/2073-7556-2023-22-4-121-126
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