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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2016-0-3-102-108</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-42</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ ЦЕРТОЛИЗУМАБА ПЭГОЛА ПРИ БОЛЕЗНИ КРОНА (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>CERTOLIZUMAB PEGOL IN CHOHN'S DISEASE (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шапина</surname><given-names>Марина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Shapina</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">shapina.mv@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халиф</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Khalif</surname><given-names>I. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нанаева</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nanaeva</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «ГНЦК им. А.Н. Рыжих» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Scientific Center of Coloproctology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>102</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шапина М.В., Халиф И.Л., Нанаева Б.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Шапина М.В., Халиф И.Л., Нанаева Б.А.</copyright-holder><copyright-holder xml:lang="en">Shapina M.V., Khalif I.L., Nanaeva V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/42">https://www.ruproctology.com/jour/article/view/42</self-uri><kwd-group xml:lang="ru"><kwd>болезнь Крона</kwd><kwd>цертолизумаб пэгол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Crohn's disease</kwd><kwd>Certolizumab pegol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wilkins T., Jarvis K., Patel J. 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