gnckКолопроктологияKoloproktologia2073-75562686-7303Russian Association of Coloproctology10.33878/2073-7556-2026-25-2-149-160gnck-2137Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWЛечение свищей прямой кишки с использованием инъекций аутологичной жировой ткани. Все ли так однозначно? (обзор литературы)Treatment of rectal fistulas using autologous fat injections. Is it really so clear? (review)КузинаЕ. А.KuzinaElizaveta A.

Кузина Елизавета Александровна — аспирант

ул. Саляма Адиля, д. 2, г. Москва, 123423

Salyama Adilya st., 2, Moscow, 123423

kuzina.elizaveta.98@gmail.comhttps://orcid.org/0000-0001-7329-7878ОмароваМ. М.OmarovaMariyam M.

Омарова Мариям Магомедовна — к.м.н., врач-колопроктолог отдела общей и реконструктивной колопроктологии

ул. Саляма Адиля, д. 2, г. Москва, 123423

Salyama Adilya st., 2, Moscow, 123423

https://orcid.org/0000-0002-1207-5988МудровА. А.MudrovAndrey A.

Мудров Андрей Анатольевич — д.м.н., ведущий научный сотрудник отдела общей и реконструктивной колопроктологии; профессор кафедры колопроктологии 

ул. Саляма Адиля, д. 2, г. Москва, 123423

ул. Баррикадная, д. 2/1, стр. 1, г. Москва, 125993

Salyama Adilya st., 2, Moscow, 123423

Barrikadnaya st., 2/1, bld. 1, Moscow, 125993

https://orcid.org/0000-0002-1636-8075ТитовА. Ю.TitovAlexander Y.

Титов Александр Юрьевич — д.м.н., руководитель отделения общей и реконструктивной колопроктологии

ул. Саляма Адиля, д. 2, г. Москва, 123423

Salyama Adilya st., 2, Moscow, 123423

https://orcid.org/0009-0007-7100-2889ОбуховВ. К.ObukhovViktor K.

Обухов Виктор Константинович — к.м.н., доцент, заведующий учебной частью кафедры колопроктологии

ул. Баррикадная, д. 2/1, стр. 1, г. Москва, 125993

Barrikadnaya st., 2/1, bld. 1, Moscow, 125993

https://orcid.org/0000-0002-1778-0571КостаревИ. В.KostarevIvan V.

Костарев Иван Васильевич — д.м.н., руководитель отдела общей и реконструктивной колопроктологии; профессор кафедры колопроктологии

ул. Саляма Адиля, д. 2, г. Москва, 123423

ул. Баррикадная, д. 2/1, стр. 1, г. Москва, 125993

Salyama Adilya st., 2, Moscow, 123423

Barrikadnaya st., 2/1, bld. 1, Moscow, 125993

ФГБУ «НМИЦ колопроктологии имени А.Н. Рыжих» Минздрава РоссииРоссияRyzhikh National Medical Research Center of ColoproctologyRussian FederationФГБУ «НМИЦ колопроктологии имени А.Н. Рыжих» Минздрава России; ФГБОУ ДПО РМАНПО Минздрава РоссииРоссияRyzhikh National Medical Research Center of Coloproctology; Russian Medical Academy of Continuous Professional EducationRussian FederationФГБОУ ДПО РМАНПО Минздрава РоссииРоссияRussian Medical Academy of Continuous Professional EducationRussian Federation202605062026252149160Copyright © Кузина Е.А., Омарова М.М., Мудров А.А., Титов А.Ю., Обухов В.К., Костарев И.В., 20262026Кузина Е.А., Омарова М.М., Мудров А.А., Титов А.Ю., Обухов В.К., Костарев И.В.Kuzina E.A., Omarova M.M., Mudrov A.A., Titov A.Y., Obukhov V.K., Kostarev I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ruproctology.com/jour/article/view/2137

В обзоре литературы освещены современные подходы к лечению сложных криптогландулярных свищей прямой кишки, приведены сводные данные, характеризующие различные показатели после использования сфинктеросберегающих вмешательств, дана оценка эффективности и безопасности применения различных методик лечения. Основной акцент публикаций направлен на существующие варианты применения клеточных технологий при лечении криптогландулярных свищей, в частности, с критической точки зрения рассмотрено использование аутологичной жировой ткани как источника мезенхимальных стволовых клеток. С учетом данных современной литературы, метод обладает большим потенциалом, является безопасным и малотравматичным при лечении сложных свищей прямой кишки. В то же время его внедрение в клиническую практику требует дополнительных исследований и унификации, как процессов приготовления, так и технологии применения.

The review evaluates current approaches to complex cryptoglandular anorectal fistulas and various outcomes following sphincter-preserving procedures, and assesses the efficacy and safety of various treatment methods. The paper primarily focus on existing applications of stem cells technologies in treatment of cryptoglandular fistulas, critical examining the use of autologous adipose tissue as a source of mesenchymal stem cells. Based on current literature, this method is safe, and minimally invasive, moreover it has significant potential, in the treatment of complex rectal fistulas. However, its implementation in clinical practice requires further research and standardization of both preparation processes and application technology.

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The authors declare that there are no conflicts of interest present.