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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2026-25-2-140-147</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-2129</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Рак сигмовидной кишки в дивертикуле (клинический случай и обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Sigmoid cancer in a diverticulum (a case report and review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3549-4499</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березовская</surname><given-names>Т. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezovskay</surname><given-names>T. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Березовская Татьяна Павловна — д.м.н., профессор, главный научный сотрудник отделения лучевой диагностики</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Tatiana P. Berezovskay </p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5961-2958</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невольских</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nevolskikh</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Невольских Алексей Алексеевич — д.м.н., заместитель директора по лечебной работе</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Alexey A. Nevolskikh</p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4524-0839</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дайнеко</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Daineko</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дайнеко Яна Александровна — к.м.н., старший научный сотрудник отделения лучевой диагностики</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Yana A. Daineko </p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2678-016X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеенко</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeenko</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеенко Виолетта Андреевна — врач-онколог отделения абдоминальной онкологии</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Violetta A. Avdeenko </p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><email xlink:type="simple">avdeenko.vita@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-2841-9870</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Резник</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Reznik</surname><given-names>I. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Резник Иван Павлович — врач-патологоанатом отдела онкопатологии</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Ivan P. Reznik </p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1908-2256</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гриневич</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grinevich</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гриневич Вячеслав Николаевич — к.м.н., заведующий отделением онкопатологии</p><p>ул. Маршала Жукова, д. 10, Калужская область, г. Обнинск, 249031</p></bio><bio xml:lang="en"><p>Vyacheslav N. Grinevich </p><p>Marshal Zhukov st., 10, Obninsk, 249031</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МРНЦ им. А.Ф. Цыба — филиал ФГБУ «НМИЦ радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.Tsyb Medical Radiological Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>05</day><month>06</month><year>2026</year></pub-date><volume>25</volume><issue>2</issue><fpage>140</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Березовская Т.П., Невольских А.А., Дайнеко Я.А., Авдеенко В.А., Резник И.П., Гриневич В.Н., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Березовская Т.П., Невольских А.А., Дайнеко Я.А., Авдеенко В.А., Резник И.П., Гриневич В.Н.</copyright-holder><copyright-holder xml:lang="en">Berezovskay T.P., Nevolskikh A., Daineko Y.A., Avdeenko V.A., Reznik I.P., Grinevich V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/2129">https://www.ruproctology.com/jour/article/view/2129</self-uri><abstract><sec><title>ЦЕЛЬ ИССЛЕДОВАНИЯ</title><p>ЦЕЛЬ ИССЛЕДОВАНИЯ: на примере клинического случая представить и обсудить сложности, возникающие в лучевой и эндоскопической диагностике рака в дивертикуле толстой кишки при обследовании больных с дивертикулитом.</p></sec><sec><title>ПАЦИЕНТЫ И МЕТОДЫ</title><p>ПАЦИЕНТЫ И МЕТОДЫ: пациентка, 76 лет, проходила клинико-инструментальное обследование по поводу обострения дивертикулярной болезни сигмовидной кишки.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ: по результатам лучевого и эндоскопического исследования выявлен хронический паракишечный инфильтрат сигмовидной кишки с вовлечением культи матки и появлением признаков опухолевого роста в дивертикуле, а также опухоль в восходящей ободочной кишке. Пациентке выполнена симультанная правосторонняя гемиколэктомия и комбинированная передняя резекция прямой кишки с экстирпацией культи матки. При патоморфологическом исследовании в просвете дивертикула выявлена низкодифференцированная аденокарцинома с признаками нарушения в системе репарации ДНК (dMMR) и опухоль восходящего отдела ободочной кишки сходного гистологического строения и иммунофенотипа.</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ: диагностика рака, возникающего в дивертикуле толстой кишки, является сложной задачей, обусловленной особенностями его роста и необходимостью дифференциации с осложненными формами дивертикулярной болезни. В подобных случаях необходимо проводить тщательное комплексное клиникоинструментальное обследование для адекватного планирования хирургического лечения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>AIM</title><p>AIM: to present and discuss the challenges of radiological and endoscopic diagnosis of cancer within a colonic diverticulum in patients with diverticulitis, using a clinical case as an example.</p></sec><sec><title>PATIENTS AND METHODS</title><p>PATIENTS AND METHODS: a 76-year-old female patient underwent clinical and instrumental examination for exacerbation of sigmoid diverticular disease.</p></sec><sec><title>RESULTS</title><p>RESULTS: based on the findings of radiological and endoscopic examinations, a chronic pericolonic inflammatory infiltrate of the sigmoid colon involving the uterine stump was identified, showing signs of neoplastic growth within a diverticulum, as well as a tumor in the ascending colon. The patient underwent simultaneous right hemicolectomy and combined anterior resection of the rectum with extirpation of the uterine stump. Pathomorphological examination revealed a poorly differentiated adenocarcinoma with signs of impaired DNA mismatch repair (dMMR) within the diverticulum, and a tumor in the ascending colon with similar characteristics.</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION: cancer arising in a colonic diverticulum presents a complex diagnostic challenge due to its unique growth patterns and the need to differentiate it from complicated forms of diverticular disease. In such cases, a thorough and comprehensive clinical and instrumental examination is necessary for adequate planning of surgical treatment.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>рак в дивертикуле толстой кишки</kwd><kwd>осложненный диверитикулит</kwd><kwd>эндоскопическое исследование</kwd><kwd>магнитно-резонансная томография</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal cancer</kwd><kwd>cancer in a diverticulum</kwd><kwd>diverticulitis</kwd><kwd>endoscopic examination</kwd><kwd>magnetic resonance imaging (MRI)</kwd><kwd>computed tomography (CT)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Левчук А.Л., Абдуллаев А.Э. Онкологическая трансформация дивертикулярной болезни толстой кишки. Сочетание или закономерный последовательный процесс? 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PMID: 8430371</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
