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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2026-25-1-149-155</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-2113</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТААНАЛИЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>META-ANALYSIS</subject></subj-group></article-categories><title-group><article-title>Антибактериальная профилактика посткоагуляционного синдрома при эндоскопическом удалении новообразований толстой кишки  (литературный обзор и метаанализ)</article-title><trans-title-group xml:lang="en"><trans-title>Antibacterial prevention of postcoagulation syndrome during endoscopic removal of colon neoplasms (review and meta-analysis)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-9472-3220</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Погосов</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pogosov</surname><given-names>Nikolay S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Погосов Николай Сергеевич — младший научный сотрудник отдела эндоскопической диагностики и хирургии</p><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya st., 2, Moscow, 123423</p></bio><email xlink:type="simple">kolia.pogosov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7342-5753</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балкаров</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balkarov</surname><given-names>Artem A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балкаров Артем Анатольевич — к.м.н., научный сотрудник, врач-онколог 3-го хирургического отделения онкопроктологии</p><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya st., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5848-4050</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ликутов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Likutov</surname><given-names>Alexey A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ликутов Алексей Александрович — к.м.н., руководитель отдела эндоскопической диагностики и хирургии</p><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p><p>ул. Баррикадная, д. 2/1, стр. 1, г. Москва, 125993</p></bio><bio xml:lang="en"><p>Salyama Adilya st., 2, Moscow, 123423</p><p>Barrikadnaya st., 2/1, Moscow, 125993</p><p> </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6876-4272</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назаров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazarov</surname><given-names>Ilya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Назаров Илья Владимирович — к.м.н., главный врач</p><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya st., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ колопроктологии имени А.Н. Рыжих» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryzhikh National Medical Research Center of Coloproctology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ колопроктологии имени А.Н. Рыжих» Минздрава России; ФГБОУ ДПО РМАНПО Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryzhikh National Medical Research Center of Coloproctology; Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2026</year></pub-date><volume>25</volume><issue>1</issue><fpage>149</fpage><lpage>155</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Погосов Н.С., Балкаров А.А., Ликутов А.А., Назаров И.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Погосов Н.С., Балкаров А.А., Ликутов А.А., Назаров И.В.</copyright-holder><copyright-holder xml:lang="en">Pogosov N.S., Balkarov A.A., Likutov A.A., Nazarov I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/2113">https://www.ruproctology.com/jour/article/view/2113</self-uri><abstract><sec><title>ЦЕЛЬ</title><p>ЦЕЛЬ: изучить эффективность антибиотикотерапии в профилактике посткоагуляционного синдрома.</p></sec><sec><title>МАТЕРИАЛЫ И МЕТОДЫ</title><p>МАТЕРИАЛЫ И МЕТОДЫ: поиск литературы и метаанализ производился в соответствии с рекомендациями PRISMA при помощи поисковой системы PUBMED в электронной базе Medline без ограничения даты публикации среди англоязычной литературы. В систематический обзор включены все исследования, посвященные антибактериальной профилактике посткоагуляционного синдрома после эндоскопического удаления эпителиальных новообразований толстой кишки.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ: в анализ включены 5 исследований — 1055 пациентов, 546 — в группе антибиотикопрофилактики и 509 — в группе без нее. Посткоагуляционный синдром значимо чаще развивался в группе пациентов без антибактериальной профилактики в сравнении с группой с использованием данного метода профилактики — 16,1% против 5,9% (ОШ = 0,30; 95% ДИ: 0,09–0,96; p = 0,04).</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ: антибиотикопрофилактика снижает частоту развития посткоагуляционного синдрома после эндоскопического удаления эпителиальных новообразований толстой кишки.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>AIM</title><p>AIM: to assess efficacy of antibacterial prevention for postcoagulation syndrome after endoscopic removal of colon neoplasms.</p></sec><sec><title>MATERIALS AND METHODS</title><p>MATERIALS AND METHODS: literature search and meta-analysis were performed in accordance with the PRISMA guidelines using the PUBMED search system in the Medline electronic database. The systematic review included all studies devoted to antibacterial prophylactic of postcoagulation syndrome after endoscopic submucosal resection neoplasms of colon.</p></sec><sec><title>RESULTS</title><p>RESULTS: the analysis included 5 studies — 1055 patients, 546 in the antibiotic prevention group and 509 in the group without it. Postcoagulation syndrome was lower in antibacterial prophylaxis group 5,9% vs 16,1% without antibacterial prevention group (OR = 0.30; 95% CI: 0,09–0,96; p = 0.04).</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION: antibiotic prophylactic reduces the incidence of postcoagulation syndrome after endoscopic removal of epithelial neoplasms of the colon.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>посткоагуляционный синдром</kwd><kwd>антибактериальная профилактика</kwd><kwd>эндоскопическое удаление эпителиальных новообразований толстой кишки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postcoagulation syndrome</kwd><kwd>antibacterial prophylactic</kwd><kwd>endoscopic removal of epithelial neoplasms of the colon</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gweon TG, Yang DH. 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