gnckКолопроктологияKoloproktologia2073-75562686-7303Russian Association of Coloproctology10.33878/2073-7556-2024-23-1-152-161gnck-1890Research ArticleОБЗОРЫ ЛИТЕРАТУРЫ И МЕТААНАЛИЗLITERATURE REVIEWS AND METAANALYSISФизические упражнения как эффективная адъювантная терапия при ремиссии воспалительных заболеваний кишечника (обзор литературы)Physical exercises as an effective adjuvant therapy of IBD in remission (review)https://orcid.org/0000-0002-4548-063XКостюкевичС. В.KostyukevichS. V.

Костюкевич Сергей Владимирович — доктор медицинских наук, заведующий кафедрой медицинской биологии

ул. Кирочная, д.41, г. Санкт-Петербург, 191015

Kirochnaya st., 41, St. Petersburg, 191015

S.Kostyukevich@szgmu.ruhttps://orcid.org/0000-0002-6151-2021БакулинИ. Г.BakulinI. G.

Бакулин Игорь Геннадьевич — профессор, доктор медицинских наук, декан лечебного факультета, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С.М. Рысса

ул. Кирочная, д.41, г. Санкт-Петербург, 191015

Kirochnaya st., 41, St. Petersburg, 191015

ФГБОУ ВО «Северо-Западный ГМУ имени И.И.Мечникова» Минздрава РоссииРоссияMechnikov North-West State Medical UniversityRussian Federation202421032024231152161Copyright © Костюкевич С.В., Бакулин И.Г., 20242024Костюкевич С.В., Бакулин И.Г.Kostyukevich S.V., Bakulin I.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ruproctology.com/jour/article/view/1890

Воспалительные заболевания кишечника (ВЗК) включают болезнь Крона и язвенный колит. ВЗК являются хроническими болезнями с траекторией ремиссии и рецидива. Медикаментозная терапия ВЗК недостаточно эффективна. Существует потребность в адъювантной терапии ВЗК. Цель настоящего обзора состояла в том, чтобы представить роль физических упражнений и их влияние на ВЗК. В этой связи ведётся поиск дополнительных инструментов для повышения частоты достижения и удержания ремиссии. В последнее время получены данные, что физическая нагрузка индуцирует каскад противовоспалительных цитокинов, специфически запускаемый за счет экспоненциального увеличения мышечного интерлейкин 6, и при регулярных тренировках в период ремиссии может снизить базальные уровни циркулирующих воспалительных маркеров и потенциально уменьшить хроническое воспаление при ВЗК. Рекомендации врача по физической активности в период ремиссии могут быть эффективны в качестве дополнительного компонента противорецидивного лечения.

Inflammatory bowel diseases (IBD) include Crohn’s disease and ulcerative colitis. IBDs are chronic diseases with a trajectory of remission and relapse. Drug therapy for IBD is not effective enough. There is a need for adjuvant therapy for IBD. The purpose of this review was to present the role of exercise and its impact on IBD. In this regard, a search is underway for additional tools to increase the frequency of achieving and maintaining remission. There is recent evidence that exercise induces a cascade of anti-inflammatory cytokines, specifically triggered by an exponential increase in muscle interleukin 6, and with regular exercise during remission may reduce basal levels of circulating inflammatory markers and potentially reduce chronic inflammation in IBD. Doctor’s recommendations for physical activity during remission can be effective as an additional component of anti-relapse treatment.

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The authors declare that there are no conflicts of interest present.