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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2023-22-1-138-146</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1782</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ И МЕТААНАЛИЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS AND METAANALYSIS</subject></subj-group></article-categories><title-group><article-title>Колоректальный рак на фоне язвенного колита (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Colorectal cancer in ulcerative colitis (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5565-615X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расулов</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Rasulov</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>1-е Успенское ш., д. 111, дер. Лапино, Московская обл.,143081</p></bio><bio xml:lang="en"><p>Arsen O. Rasulov </p><p>1st Uspenskoe Shosse, 111, Lapino, Moscow region, 143081</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3024-9283</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликов Артур Эдуардович</p><p>1-е Успенское ш., д. 111, дер. Лапино, Московская обл.,143081</p></bio><bio xml:lang="en"><p>Artur E. Kulikov </p><p>1st Uspenskoe Shosse, 111, Lapino, Moscow region, 143081</p></bio><email xlink:type="simple">Kulikov_A.E._MD@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9992-3822</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мадьяров</surname><given-names>Ж. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Madyarov</surname><given-names>J. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>1-е Успенское ш., д. 111, дер. Лапино, Московская обл.,143081</p></bio><bio xml:lang="en"><p>Jasur M. Madyarov </p><p>1st Uspenskoe Shosse, 111, Lapino, Moscow region, 143081</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2306-407X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расулов</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rasulov</surname><given-names>Z. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>1-е Успенское ш., д. 111, дер. Лапино, Московская обл.,143081</p></bio><bio xml:lang="en"><p>Zaur R. Rasulov </p><p>1st Uspenskoe Shosse, 111, Lapino, Moscow region, 143081</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клинический госпиталь «Лапино» группы компаний «Мать и дитя»</institution></aff><aff xml:lang="en"><institution>Clinical Hospital “Lapino” of the “Mother and Child” Group of companies</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>03</month><year>2023</year></pub-date><volume>22</volume><issue>1</issue><fpage>138</fpage><lpage>146</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Расулов А.О., Куликов А.Э., Мадьяров Ж.М., Расулов З.Р., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Расулов А.О., Куликов А.Э., Мадьяров Ж.М., Расулов З.Р.</copyright-holder><copyright-holder xml:lang="en">Rasulov A.O., Kulikov A.E., Madyarov J.M., Rasulov Z.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1782">https://www.ruproctology.com/jour/article/view/1782</self-uri><abstract><p>Язвенный колит (ЯК) — воспалительное заболевание кишечника, поражающее в основном людей молодого возраста. Одним из осложнений ЯК является развитие колоректального рака (КРР). В данном обзоре лите- ратуры рассмотрены эпидемиология, факторы риска развития, диагностика и скрининг, а также лекар- ственная профилактика КРР на фоне ЯК. Кроме того, описана тактика при дисплазии на фоне ЯК и раз- личные варианты хирургического лечения при развитии КРР. Учитывая недостаточность литературных данных для окончательного суждения о подходах к лечению рака толстой кишки (особенно прямой кишки) на фоне ЯК, достаточно актуальным представляется проведение дальнейших исследований по оценке как онкологических, так и функциональных результатов лечения, что может помочь в решении этой важной проблемы.</p></abstract><trans-abstract xml:lang="en"><p>Ulcerative colitis (UC) is an inflammatory bowel disease that mainly affects young people. Colorectal cancer (CRC) is one of the UC complications. This review considers the epidemiology, risk factors, diagnosis and screening, and drug prevention of CRC in UC. Various treatment options for dysplasia and CRC associated with UC are described. Taking into account the lack of literature to standardize colorectal cancer treatment approaches (especially rectal cancer) for UC, further studies are warranted to evaluate both oncological and functional treatment outcomes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>язвенный колит</kwd><kwd>дисплазия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal cancer</kwd><kwd>ulcerative colitis</kwd><kwd>dysplasia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sung H, Ferlay J, Siegel RL et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209–49. doi: 10.3322/CAAC.21660</mixed-citation><mixed-citation xml:lang="en">Sung H, Ferlay J, Siegel RL et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209–49. doi: 10.3322/CAAC.21660</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Шелыгин Ю.А., Халиф И.Л., и соавт. Клинические рекомендации Российской гастроэнтерологической ассоциации и Ассоциации колопроктологов России по диагностике и лечению язвенного колита. Колопроктология. 2017:6–30. doi: 10.33878/2073-7556-2017-0-1</mixed-citation><mixed-citation xml:lang="en">Ivashkin V.T., Shelygin Yu.A., Khalif I.L. et al. Clinical guide of Russian association of gastroenterology and Russian Association of coloproctology on diagnostics and treatment of ulcerative colitis. Koloproctologia. 2017:6–30. (in Russ.). doi: 10.33878/2073-7556-2017-0-1</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kaplan GG, Ng SC. Understanding and Preventing the Global Increase of Inflammatory Bowel Disease. Gastroenterology. 2017;152:313–321.e2. doi: 10.1053/J.GASTRO.2016.10.020</mixed-citation><mixed-citation xml:lang="en">Kaplan GG, Ng SC. Understanding and Preventing the Global Increase of Inflammatory Bowel Disease. Gastroenterology. 2017;152:313–321.e2. doi: 10.1053/J.GASTRO.2016.10.020</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Jess T, Simonsen J, Jorgensen KT, Pedersen BV, Nielsen NM, Frisch M. Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 years. Gastroenterology. 2012;143:375–381. e1. doi: 10.1053/J.GASTRO.2012.04.016</mixed-citation><mixed-citation xml:lang="en">Jess T, Simonsen J, Jorgensen KT, Pedersen BV, Nielsen NM, Frisch M. Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 years. Gastroenterology. 2012;143:375–381. e1. doi: 10.1053/J.GASTRO.2012.04.016</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Triantafillidis JK, Nasioulas G, Kosmidis PA. Colorectal Cancer and Inflammatory Bowel Disease: Epidemiology, Risk Factors, Mechanisms of Carcinogenesis and Prevention Strategies. Anticancer Research. Anticancer Res. 2009;29:2727–38.</mixed-citation><mixed-citation xml:lang="en">Triantafillidis JK, Nasioulas G, Kosmidis PA. Colorectal Cancer and Inflammatory Bowel Disease: Epidemiology, Risk Factors, Mechanisms of Carcinogenesis and Prevention Strategies. Anticancer Research. Anticancer Res. 2009;29:2727–38.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kulaylat MN, Dayton MT. Ulcerative colitis and cancer. J Surg Oncol. 2010;101:706–12. doi: 10.1002/JSO.21505</mixed-citation><mixed-citation xml:lang="en">Kulaylat MN, Dayton MT. Ulcerative colitis and cancer. J Surg Oncol. 2010;101:706–12. doi: 10.1002/JSO.21505</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, et al. Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2015;13:322. doi: 10.1016/J.CGH.2014.07.018</mixed-citation><mixed-citation xml:lang="en">Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, et al. Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2015;13:322. doi: 10.1016/J.CGH.2014.07.018</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Sensi B, Bagaglini G, Bellato V, Cerbo D, et al. Management of Low Rectal Cancer Complicating Ulcerative Colitis: Proposal of a Treatment Algorithm. Cancers (Basel). 2021;13. doi: 10.3390/CANCERS13102350</mixed-citation><mixed-citation xml:lang="en">Sensi B, Bagaglini G, Bellato V, Cerbo D, et al. Management of Low Rectal Cancer Complicating Ulcerative Colitis: Proposal of a Treatment Algorithm. Cancers (Basel). 2021;13. doi: 10.3390/CANCERS13102350</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Delaunoit T, Limburg PJ, Goldberg RM, Lymp JF, et al. Colorectal cancer prognosis among patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2006;4:335–42. doi: 10.1016/J.CGH.2005.12.035</mixed-citation><mixed-citation xml:lang="en">Delaunoit T, Limburg PJ, Goldberg RM, Lymp JF, et al. Colorectal cancer prognosis among patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2006;4:335–42. doi: 10.1016/J.CGH.2005.12.035</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Rutter MD, Saunders BP, Wilkinson KH, Rumbles S, et al. Thirtyyear analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology. 2006;130:1030–8. doi: 10.1053/J.GASTRO.2005.12.035</mixed-citation><mixed-citation xml:lang="en">Rutter MD, Saunders BP, Wilkinson KH, Rumbles S, et al. Thirtyyear analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology. 2006;130:1030–8. doi: 10.1053/J.GASTRO.2005.12.035</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Dulai PS, Sandborn WJ, Gupta S. Colorectal cancer and dysplasia in inflammatory bowel disease: a review of disease epidemiology, pathophysiology, and management. Cancer Prev Res (Phila). 2016;9:887. doi: 10.1158/1940-6207.CAPR-16-0124</mixed-citation><mixed-citation xml:lang="en">Dulai PS, Sandborn WJ, Gupta S. Colorectal cancer and dysplasia in inflammatory bowel disease: a review of disease epidemiology, pathophysiology, and management. Cancer Prev Res (Phila). 2016;9:887. doi: 10.1158/1940-6207.CAPR-16-0124</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nebbia M, Yassin NA, Spinelli A. Colorectal Cancer in Inflammatory Bowel Disease. Clin Colon Rectal Surg. 2020;33:305–17. doi: 10.1055/S-0040-1713748</mixed-citation><mixed-citation xml:lang="en">Nebbia M, Yassin NA, Spinelli A. Colorectal Cancer in Inflammatory Bowel Disease. Clin Colon Rectal Surg. 2020;33:305–17. doi: 10.1055/S-0040-1713748</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut. 2001;48:526. doi: 10.1136/GUT.48.4.526</mixed-citation><mixed-citation xml:lang="en">Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut. 2001;48:526. doi: 10.1136/GUT.48.4.526</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Söderlund S, Brandt L, Lapidus A, Karlén P, et al. Decreasing time-trends of colorectal cancer in a large cohort of patients with inflammatory bowel disease. Gastroenterology. 2009;136:1561–7. doi: 10.1053/J.GASTRO.2009.01.064</mixed-citation><mixed-citation xml:lang="en">Söderlund S, Brandt L, Lapidus A, Karlén P, et al. Decreasing time-trends of colorectal cancer in a large cohort of patients with inflammatory bowel disease. Gastroenterology. 2009;136:1561–7. doi: 10.1053/J.GASTRO.2009.01.064</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Dyson JK, Rutter MD. Colorectal cancer in inflammatory bowel disease: What is the real magnitude of the risk? World J Gastroenterol. 2012;18:3839. doi: 10.3748/WJG.V18.I29.3839</mixed-citation><mixed-citation xml:lang="en">Dyson JK, Rutter MD. Colorectal cancer in inflammatory bowel disease: What is the real magnitude of the risk? World J Gastroenterol. 2012;18:3839. doi: 10.3748/WJG.V18.I29.3839</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Itzkowitz SH, Present DH, Binder V, Boland CR, et al. Consensus conference: Colorectal cancer screening and surveillance in inflammatory bowel disease. Inflamm Bowel Dis. 2005;11:314–21. doi: 10.1097/01.MIB.0000160811.76729.D5</mixed-citation><mixed-citation xml:lang="en">Itzkowitz SH, Present DH, Binder V, Boland CR, et al. Consensus conference: Colorectal cancer screening and surveillance in inflammatory bowel disease. Inflamm Bowel Dis. 2005;11:314–21. doi: 10.1097/01.MIB.0000160811.76729.D5</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Reznicek E, Arfeen M, Shen B, Ghouri Y. Colorectal Dysplasia and Cancer Surveillance in Ulcerative Colitis. Dis (Basel, Switzerland). 2021;9:86. doi: 10.3390/DISEASES9040086</mixed-citation><mixed-citation xml:lang="en">Reznicek E, Arfeen M, Shen B, Ghouri Y. Colorectal Dysplasia and Cancer Surveillance in Ulcerative Colitis. Dis (Basel, Switzerland). 2021;9:86. doi: 10.3390/DISEASES9040086</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Collins PD. Strategies for detecting colon cancer and dysplasia in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013;19:860–3. doi: 10.1097/MIB.0B013E3182802C6A</mixed-citation><mixed-citation xml:lang="en">Collins PD. Strategies for detecting colon cancer and dysplasia in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013;19:860–3. doi: 10.1097/MIB.0B013E3182802C6A</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Collins PD, Mpofu C, Watson AJ, Rhodes JM. Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease. Cochrane Database Syst Rev. 2006. doi: 10.1002/14651858.CD000279.PUB3</mixed-citation><mixed-citation xml:lang="en">Collins PD, Mpofu C, Watson AJ, Rhodes JM. Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease. Cochrane Database Syst Rev. 2006. doi: 10.1002/14651858.CD000279.PUB3</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Lutgens M, Oldenburg B, Siersema PD, Van Bodegraven AA, et al. Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Br J Cancer. 2009;101:1671. doi: 10.1038/SJ.BJC.6605359</mixed-citation><mixed-citation xml:lang="en">Lutgens M, Oldenburg B, Siersema PD, Van Bodegraven AA, et al. Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Br J Cancer. 2009;101:1671. doi: 10.1038/SJ.BJC.6605359</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Adamina M, Angriman I, Bemelman WA, Biancone L, et al. European evidence based consensus on surgery for ulcerative colitis. J Crohns Colitis. 2015;9:4–25. doi: 10.1016/J.CROHNS.2014.08.012</mixed-citation><mixed-citation xml:lang="en">Adamina M, Angriman I, Bemelman WA, Biancone L, et al. European evidence based consensus on surgery for ulcerative colitis. J Crohns Colitis. 2015;9:4–25. doi: 10.1016/J.CROHNS.2014.08.012</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Kim ER, Chang DK. Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis. World J Gastroenterol. 2014;20:9872. doi: 10.3748/WJG.V20.I29.9872</mixed-citation><mixed-citation xml:lang="en">Kim ER, Chang DK. Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis. World J Gastroenterol. 2014;20:9872. doi: 10.3748/WJG.V20.I29.9872</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Pulusu SSR, Lawrance IC. Dysplasia and colorectal cancer surveillance in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol. 2017;11:711–22. doi: 10.1080/17474124.2017.1327347</mixed-citation><mixed-citation xml:lang="en">Pulusu SSR, Lawrance IC. Dysplasia and colorectal cancer surveillance in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol. 2017;11:711–22. doi: 10.1080/17474124.2017.1327347</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Kiesslich R, Fritsch J, Holtmann M, Koehler HH, et al. Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis. Gastroenterology. 2003;124:880–8. doi: 10.1053/GAST.2003.50146</mixed-citation><mixed-citation xml:lang="en">Kiesslich R, Fritsch J, Holtmann M, Koehler HH, et al. Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis. Gastroenterology. 2003;124:880–8. doi: 10.1053/GAST.2003.50146</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Lakatos PL, Lakatos L. Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies. World J Gastroenterol. 2008;14:3937. doi: 10.3748/WJG.14.3937</mixed-citation><mixed-citation xml:lang="en">Lakatos PL, Lakatos L. Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies. World J Gastroenterol. 2008;14:3937. doi: 10.3748/WJG.14.3937</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Riddell RH, Goldman H, Ransohoff DF, Appelman HD, et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol. 1983;14:931–68. doi: 10.1016/S0046-8177(83)80175-0</mixed-citation><mixed-citation xml:lang="en">Riddell RH, Goldman H, Ransohoff DF, Appelman HD, et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol. 1983;14:931–68. doi: 10.1016/S0046-8177(83)80175-0</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Navaneethan U, Jegadeesan R, Gutierrez NG, Venkatesh PGK, et al. Progression of low-grade dysplasia to advanced neoplasia based on the location and morphology of dysplasia in ulcerative colitis patients with extensive colitis under colonoscopic surveillance. J Crohns Colitis. 2013;7. doi: 10.1016/J.CROHNS.2013.06.006</mixed-citation><mixed-citation xml:lang="en">Navaneethan U, Jegadeesan R, Gutierrez NG, Venkatesh PGK, et al. Progression of low-grade dysplasia to advanced neoplasia based on the location and morphology of dysplasia in ulcerative colitis patients with extensive colitis under colonoscopic surveillance. J Crohns Colitis. 2013;7. doi: 10.1016/J.CROHNS.2013.06.006</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Heuschen UA, Hinz U, Allemeyer EH, Stern J, et al. Backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitis. Gastroenterology. 2001;120:841–7. doi: 10.1053/GAST.2001.22434</mixed-citation><mixed-citation xml:lang="en">Heuschen UA, Hinz U, Allemeyer EH, Stern J, et al. Backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitis. Gastroenterology. 2001;120:841–7. doi: 10.1053/GAST.2001.22434</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hurlstone DP, Sanders DS, Atkinson R, Hunter MD, et al. Endoscopic mucosal resection for flat neoplasia in chronic ulcerative colitis: can we change the endoscopic management paradigm? Gut. 2007;56:838. doi: 10.1136/GUT.2006.106294</mixed-citation><mixed-citation xml:lang="en">Hurlstone DP, Sanders DS, Atkinson R, Hunter MD, et al. Endoscopic mucosal resection for flat neoplasia in chronic ulcerative colitis: can we change the endoscopic management paradigm? Gut. 2007;56:838. doi: 10.1136/GUT.2006.106294</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Annese V, Daperno M, Rutter MD, Amiot A, et al. European evidence based consensus for endoscopy in inflammatory bowel disease. J Crohns Colitis. 2013;7:982–1018. doi: 10.1016/J.CROHNS.2013.09.016</mixed-citation><mixed-citation xml:lang="en">Annese V, Daperno M, Rutter MD, Amiot A, et al. European evidence based consensus for endoscopy in inflammatory bowel disease. J Crohns Colitis. 2013;7:982–1018. doi: 10.1016/J.CROHNS.2013.09.016</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Laine L, Kaltenbach T, Barkun A, McQuaid KR, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastroenterology. 2015;148:639–651.e28. doi: 10.1053/J.GASTRO.2015.01.031</mixed-citation><mixed-citation xml:lang="en">Laine L, Kaltenbach T, Barkun A, McQuaid KR, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastroenterology. 2015;148:639–651.e28. doi: 10.1053/J.GASTRO.2015.01.031</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Moss A, Bourke MJ, Williams SJ, Hourigan LF, et al. Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. Gastroenterology. 2011;140:1909–18. doi: 10.1053/J.GASTRO.2011.02.062</mixed-citation><mixed-citation xml:lang="en">Moss A, Bourke MJ, Williams SJ, Hourigan LF, et al. Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. Gastroenterology. 2011;140:1909–18. doi: 10.1053/J.GASTRO.2011.02.062</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Dignass A, Eliakim R, Magro F, Maaser C, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis. J Crohns Colitis. 2012;6:965–90. doi: 10.1016/J.CROHNS.2012.09.003</mixed-citation><mixed-citation xml:lang="en">Dignass A, Eliakim R, Magro F, Maaser C, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis. J Crohns Colitis. 2012;6:965–90. doi: 10.1016/J.CROHNS.2012.09.003</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Farraye FA, Odze RD, Eaden J, SH I, et al. AGA medical position statement on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease. Gastroenterology. 2010;138:738–45. doi: 10.1053/J.GASTRO.2009.12.037</mixed-citation><mixed-citation xml:lang="en">Farraye FA, Odze RD, Eaden J, SH I, et al. AGA medical position statement on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease. Gastroenterology. 2010;138:738–45. doi: 10.1053/J.GASTRO.2009.12.037</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Feakins RM. Inflammatory bowel disease biopsies: updated British Society of Gastroenterology reporting guidelines. J Clin Pathol. 2013;66:1005–26. doi: 10.1136/JCLINPATH-2013-201885</mixed-citation><mixed-citation xml:lang="en">Feakins RM. Inflammatory bowel disease biopsies: updated British Society of Gastroenterology reporting guidelines. J Clin Pathol. 2013;66:1005–26. doi: 10.1136/JCLINPATH-2013-201885</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Ullman TA, Croog V, Harpaz N, Sachar D, et al. Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis. Gastroenterology. 2003;125:1311–9. doi: 10.1016/J.GASTRO.2003.08.023</mixed-citation><mixed-citation xml:lang="en">Ullman TA, Croog V, Harpaz N, Sachar D, et al. Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis. Gastroenterology. 2003;125:1311–9. doi: 10.1016/J.GASTRO.2003.08.023</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">O’Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg. 2004;187:343–8. doi: 10.1016/J.AMJSURG.2003.12.020</mixed-citation><mixed-citation xml:lang="en">O’Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg. 2004;187:343–8. doi: 10.1016/J.AMJSURG.2003.12.020</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Carbonnel F, Gargouri D, Lémann M, Beaugerie L, et al. Predictive factors of outcome of intensive intravenous treatment for attacks of ulcerative colitis. Aliment Pharmacol Ther. 2000;14:273–9. doi: 10.1046/J.1365-2036.2000.00705.X</mixed-citation><mixed-citation xml:lang="en">Carbonnel F, Gargouri D, Lémann M, Beaugerie L, et al. Predictive factors of outcome of intensive intravenous treatment for attacks of ulcerative colitis. Aliment Pharmacol Ther. 2000;14:273–9. doi: 10.1046/J.1365-2036.2000.00705.X</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Pellino G, Keller DS, Sampietro GM, Carvello M, et al. Inflammatory bowel disease position statement of the Italian Society of Colorectal Surgery (SICCR): ulcerative colitis. Tech Coloproctol. 2020;24:397– 419. doi: 10.1007/S10151-020-02175-Z</mixed-citation><mixed-citation xml:lang="en">Pellino G, Keller DS, Sampietro GM, Carvello M, et al. Inflammatory bowel disease position statement of the Italian Society of Colorectal Surgery (SICCR): ulcerative colitis. Tech Coloproctol. 2020;24:397– 419. doi: 10.1007/S10151-020-02175-Z</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Pellino G, Keller DS, Sampietro GM, Annese V, et al. Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management. Tech Coloproctol. 2020;24:105–26. doi: 10.1007/S10151-019-02145-0</mixed-citation><mixed-citation xml:lang="en">Pellino G, Keller DS, Sampietro GM, Annese V, et al. Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management. Tech Coloproctol. 2020;24:105–26. doi: 10.1007/S10151-019-02145-0</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Frontali A, Cohen L, Bridoux V, Myrelid P, et al. Segmental Colectomy for Ulcerative Colitis: Is There a Place in Selected Patients Without Active Colitis? An International Multicentric Retrospective Study in 72 Patients. J Crohns Colitis. 2020;14:1687– 92. doi: 10.1093/ECCO-JCC/JJAA107</mixed-citation><mixed-citation xml:lang="en">Frontali A, Cohen L, Bridoux V, Myrelid P, et al. Segmental Colectomy for Ulcerative Colitis: Is There a Place in Selected Patients Without Active Colitis? An International Multicentric Retrospective Study in 72 Patients. J Crohns Colitis. 2020;14:1687– 92. doi: 10.1093/ECCO-JCC/JJAA107</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Khan N, Cole E, Shah Y, Paulson EC. Segmental resection is a safe oncological alternative to total proctocolectomy in elderly patients with ulcerative colitis and malignancy. Colorectal Dis. 2017;19:1108–16. doi: 10.1111/CODI.13721</mixed-citation><mixed-citation xml:lang="en">Khan N, Cole E, Shah Y, Paulson EC. Segmental resection is a safe oncological alternative to total proctocolectomy in elderly patients with ulcerative colitis and malignancy. Colorectal Dis. 2017;19:1108–16. doi: 10.1111/CODI.13721</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Connelly TM, Koltun WA. The surgical treatment of inflammatory bowel disease-associated dysplasia. Expert Rev Gastroenterol Hepatol. 2013;7:307–22. doi: 10.1586/EGH.13.17</mixed-citation><mixed-citation xml:lang="en">Connelly TM, Koltun WA. The surgical treatment of inflammatory bowel disease-associated dysplasia. Expert Rev Gastroenterol Hepatol. 2013;7:307–22. doi: 10.1586/EGH.13.17</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Caini S, Bagnoli S, Palli D, Saieva C, et al. Total and cancer mortality in a cohort of ulcerative colitis and Crohn’s disease patients: The Florence inflammatory bowel disease study, 1978-2010. Dig Liver Dis. 2016;48:1162–7. doi: 10.1016/J.DLD.2016.07.008</mixed-citation><mixed-citation xml:lang="en">Caini S, Bagnoli S, Palli D, Saieva C, et al. Total and cancer mortality in a cohort of ulcerative colitis and Crohn’s disease patients: The Florence inflammatory bowel disease study, 1978-2010. Dig Liver Dis. 2016;48:1162–7. doi: 10.1016/J.DLD.2016.07.008</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, et al. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol Off J Eur Soc Med Oncol. 2017;28:iv22–40. doi: 10.1093/ANNONC/MDX224</mixed-citation><mixed-citation xml:lang="en">Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, et al. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol Off J Eur Soc Med Oncol. 2017;28:iv22–40. doi: 10.1093/ANNONC/MDX224</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Sica GS, Biancone L. Surgery for inflammatory bowel disease in the era of laparoscopy. World J Gastroenterol. 2013;19:2445. doi: 10.3748/WJG.V19.I16.2445</mixed-citation><mixed-citation xml:lang="en">Sica GS, Biancone L. Surgery for inflammatory bowel disease in the era of laparoscopy. World J Gastroenterol. 2013;19:2445. doi: 10.3748/WJG.V19.I16.2445</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Remzi FH, Preen M. Rectal cancer and ulcerative colitis: does it change the therapeutic approach? Colorectal Dis. 2003;5:483–5. doi: 10.1046/J.1463-1318.2003.00505.X</mixed-citation><mixed-citation xml:lang="en">Remzi FH, Preen M. Rectal cancer and ulcerative colitis: does it change the therapeutic approach? Colorectal Dis. 2003;5:483–5. doi: 10.1046/J.1463-1318.2003.00505.X</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Merchea A, Wolff BG, Dozois EJ, Abdelsattar ZM, et al. Clinical features and oncologic outcomes in patients with rectal cancer and ulcerative colitis: a single-institution experience. Dis Colon Rectum. 2012;55:881–5. doi: 10.1097/DCR.0B013E31825BF779</mixed-citation><mixed-citation xml:lang="en">Merchea A, Wolff BG, Dozois EJ, Abdelsattar ZM, et al. Clinical features and oncologic outcomes in patients with rectal cancer and ulcerative colitis: a single-institution experience. Dis Colon Rectum. 2012;55:881–5. doi: 10.1097/DCR.0B013E31825BF779</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Monson JRT, Weiser MR, Buie WD, et al. Practice parameters for the management of rectal cancer (revised). Dis Colon Rectum. 2013;56:535–50. doi: 10.1097/DCR.0B013E31828CB66C</mixed-citation><mixed-citation xml:lang="en">Monson JRT, Weiser MR, Buie WD, et al. Practice parameters for the management of rectal cancer (revised). Dis Colon Rectum. 2013;56:535–50. doi: 10.1097/DCR.0B013E31828CB66C</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Song DY, Lawrie WT, Abrams RA, Kafonek DR, et al. Acute and late radiotherapy toxicity in patients with inflammatory bowel disease. Int J Radiat Oncol Biol Phys. 2001;51:455–9. doi: 10.1016/S0360-3016(01)01629-7</mixed-citation><mixed-citation xml:lang="en">Song DY, Lawrie WT, Abrams RA, Kafonek DR, et al. Acute and late radiotherapy toxicity in patients with inflammatory bowel disease. Int J Radiat Oncol Biol Phys. 2001;51:455–9. doi: 10.1016/S0360-3016(01)01629-7</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Spinelli A, Carvello M, Kotze PG, Maroli A, et al. Ileal pouch-anal anastomosis with fluorescence angiography: a case-matched study. Colorectal Dis. 2019;21:827–32. doi: 10.1111/CODI.14611</mixed-citation><mixed-citation xml:lang="en">Spinelli A, Carvello M, Kotze PG, Maroli A, et al. Ileal pouch-anal anastomosis with fluorescence angiography: a case-matched study. Colorectal Dis. 2019;21:827–32. doi: 10.1111/CODI.14611</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Zmora O, Spector D, Dotan I, Klausner JM, et al. Is stapled ileal pouch anal anastomosis a safe option in ulcerative colitis patients with dysplasia or cancer? Int J Colorectal Dis. 2009;24:1181–6. doi: 10.1007/S00384-009-0744-9</mixed-citation><mixed-citation xml:lang="en">Zmora O, Spector D, Dotan I, Klausner JM, et al. Is stapled ileal pouch anal anastomosis a safe option in ulcerative colitis patients with dysplasia or cancer? Int J Colorectal Dis. 2009;24:1181–6. doi: 10.1007/S00384-009-0744-9</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Inoue Y, Araki T, Okugawa Y, KawamotoA, et al. Chemoradiotherapy followed by restorative proctocolectomy with partial intersphincteric resection for advanced rectal cancer associated with ulcerative colitis: report of a case. Surg Today. 2014;44:387–90. doi: 10.1007/S00595-013-0558-9</mixed-citation><mixed-citation xml:lang="en">Inoue Y, Araki T, Okugawa Y, KawamotoA, et al. Chemoradiotherapy followed by restorative proctocolectomy with partial intersphincteric resection for advanced rectal cancer associated with ulcerative colitis: report of a case. Surg Today. 2014;44:387–90. doi: 10.1007/S00595-013-0558-9</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Williams NS, Dixon MF, Johnston D. Reappraisal of the 5 centimetre rule of distal excision for carcinoma of the rectum: a study of distal intramural spread and of patients’ survival. Br J Surg. 1983;70:150–4. doi: 10.1002/BJS.1800700305</mixed-citation><mixed-citation xml:lang="en">Williams NS, Dixon MF, Johnston D. Reappraisal of the 5 centimetre rule of distal excision for carcinoma of the rectum: a study of distal intramural spread and of patients’ survival. Br J Surg. 1983;70:150–4. doi: 10.1002/BJS.1800700305</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Guillem JG, Chessin DB, Shia J, Suriawinata A, et al. A Prospective Pathologic Analysis Using Whole-Mount Sections of Rectal Cancer Following Preoperative Combined Modality Therapy: Implications for Sphincter Preservation. Ann Surg. 2007;245:88. doi: 10.1097/01.SLA.0000232540.82364.43</mixed-citation><mixed-citation xml:lang="en">Guillem JG, Chessin DB, Shia J, Suriawinata A, et al. A Prospective Pathologic Analysis Using Whole-Mount Sections of Rectal Cancer Following Preoperative Combined Modality Therapy: Implications for Sphincter Preservation. Ann Surg. 2007;245:88. doi: 10.1097/01.SLA.0000232540.82364.43</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Hotta S, Shimada Y, Nakano M, Yamada S, et al. Feasibility of restorative proctocolectomy in patients with ulcerative colitisassociated lower rectal cancer: A retrospective study. Asian J Surg. 2019;42:267–73. doi: 10.1016/J.ASJSUR.2018.01.003</mixed-citation><mixed-citation xml:lang="en">Hotta S, Shimada Y, Nakano M, Yamada S, et al. Feasibility of restorative proctocolectomy in patients with ulcerative colitisassociated lower rectal cancer: A retrospective study. Asian J Surg. 2019;42:267–73. doi: 10.1016/J.ASJSUR.2018.01.003</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Fazio VW, Kiran RP, Remzi FH, Coffey JC, et al. Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg. 2013;257:679–85. doi: 10.1097/SLA.0b013e31827d99a2</mixed-citation><mixed-citation xml:lang="en">Fazio VW, Kiran RP, Remzi FH, Coffey JC, et al. Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg. 2013;257:679–85. doi: 10.1097/SLA.0b013e31827d99a2</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Rouanet P, Rivoire M, Gourgou S, Lelong B, et al. Sphinctersaving surgery for ultra-low rectal carcinoma initially indicated for abdominoperineal resection: Is it safe on a long-term follow-up? J Surg Oncol. 2021;123:299–310. doi: 10.1002/JSO.26249</mixed-citation><mixed-citation xml:lang="en">Rouanet P, Rivoire M, Gourgou S, Lelong B, et al. Sphinctersaving surgery for ultra-low rectal carcinoma initially indicated for abdominoperineal resection: Is it safe on a long-term follow-up? J Surg Oncol. 2021;123:299–310. doi: 10.1002/JSO.26249</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Park JS, Park SY, Kim HJ, Cho SH, et al. Long-term Oncologic Outcomes After Neoadjuvant Chemoradiation Followed by Intersphincteric Resection With Coloanal Anastomosis for Locally Advanced Low Rectal Cancer. Dis Colon Rectum. 2019;62:408–16. doi: 10.1097/DCR.0000000000001321</mixed-citation><mixed-citation xml:lang="en">Park JS, Park SY, Kim HJ, Cho SH, et al. Long-term Oncologic Outcomes After Neoadjuvant Chemoradiation Followed by Intersphincteric Resection With Coloanal Anastomosis for Locally Advanced Low Rectal Cancer. Dis Colon Rectum. 2019;62:408–16. doi: 10.1097/DCR.0000000000001321</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Lorenzi B, Brading AF, Martellucci J, Cetta F, et al. Short-term effects of neoadjuvant chemoradiotherapy on internal anal sphincter function: a human in vitro study. Dis Colon Rectum. 2012;55:465–72. doi: 10.1097/DCR.0B013E31824154A0</mixed-citation><mixed-citation xml:lang="en">Lorenzi B, Brading AF, Martellucci J, Cetta F, et al. Short-term effects of neoadjuvant chemoradiotherapy on internal anal sphincter function: a human in vitro study. Dis Colon Rectum. 2012;55:465–72. doi: 10.1097/DCR.0B013E31824154A0</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Ito M, Saito N, Sugito M, Kobayashi A, et al. Analysis of clinical factors associated with anal function after intersphincteric resection for very low rectal cancer. Dis Colon Rectum. 2009;52:64–70. doi: 10.1007/DCR.0B013E31819739A0</mixed-citation><mixed-citation xml:lang="en">Ito M, Saito N, Sugito M, Kobayashi A, et al. Analysis of clinical factors associated with anal function after intersphincteric resection for very low rectal cancer. Dis Colon Rectum. 2009;52:64–70. doi: 10.1007/DCR.0B013E31819739A0</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Reynolds IS, O’Toole A, Deasy J, McNamara DA, et al. A meta-analysis of the clinicopathological characteristics and survival outcomes of inflammatory bowel disease associated colorectal cancer. Int J Colorectal Dis. 2017;32:443–51. doi: 10.1007/S00384-017-2754-3</mixed-citation><mixed-citation xml:lang="en">Reynolds IS, O’Toole A, Deasy J, McNamara DA, et al. A meta-analysis of the clinicopathological characteristics and survival outcomes of inflammatory bowel disease associated colorectal cancer. Int J Colorectal Dis. 2017;32:443–51. doi: 10.1007/S00384-017-2754-3</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Thicoïpé A, Laharie D, Smith D, Chabrun E, et al. Oncological outcomes of IBD-associated versus sporadic colorectal cancer in modern era: a matched case-control study. Int J Colorectal Dis. 2018;33:963–6. doi: 10.1007/S00384-018-3049-Z</mixed-citation><mixed-citation xml:lang="en">Thicoïpé A, Laharie D, Smith D, Chabrun E, et al. Oncological outcomes of IBD-associated versus sporadic colorectal cancer in modern era: a matched case-control study. Int J Colorectal Dis. 2018;33:963–6. doi: 10.1007/S00384-018-3049-Z</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
