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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2022-21-4-68-76</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1734</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Результаты хирургического лечения больных с метастазами колоректального рака в забрюшинные и тазовые лимфатические узлы</article-title><trans-title-group xml:lang="en"><trans-title>Surgery for retroperitoneal and pelvic lymph node metastases of colorectal cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7203-1859</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономаренко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomarenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3746-5218</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хильков</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khilkov</surname><given-names>Yury S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><email xlink:type="simple">yurii.hilkov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4384-3668</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панина</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arzamastseva</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1730-3070</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арзамасцева</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Panina</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9294-5447</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачкасов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3919-9067</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбаков</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakov</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "НМИЦ колопроктологии имени А.Н.Рыжих" Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryzhikh National Medical Research Center of Coloproctology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>21</day><month>12</month><year>2022</year></pub-date><volume>21</volume><issue>4</issue><fpage>68</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пономаренко А.А., Хильков Ю.С., Панина М.В., Арзамасцева А.И., Ачкасов С.И., Рыбаков Е.Г., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Пономаренко А.А., Хильков Ю.С., Панина М.В., Арзамасцева А.И., Ачкасов С.И., Рыбаков Е.Г.</copyright-holder><copyright-holder xml:lang="en">Ponomarenko A.A., Khilkov Y.S., Arzamastseva A.I., Panina M.V., Achkasov S.I., Rybakov E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1734">https://www.ruproctology.com/jour/article/view/1734</self-uri><abstract><sec><title>ВВЕДЕНИЕ</title><p>ВВЕДЕНИЕ: в настоящее время не разработана тактика лечения пациентов с метастатически пораженными забрюшинными лимфоузлами.</p></sec><sec><title>ЦЕЛЬ ИССЛЕДОВАНИЯ</title><p>ЦЕЛЬ ИССЛЕДОВАНИЯ: оценить влияние хирургического лечение при метастазах в забрюшинных и тазовых лимфоузлах на общую и безрецидивную выживаемость.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ: в анализ включено 30 пациентов с метастазами в забрюшинные лимфоузлы, находившихся на лечении в период с января 2016 по октябрь 2019 гг., среди которых колоректальный рак, с синхронными метастазами в забрюшинные лимфоузлы, диагностирован в 21/30 (70%). Медиана общей и безрецидивной выживаемости, у пациентов, перенесших лимфодиссекцию, составила 32 и 13 месяцев, соответственно. Рецидивы возникли у 14/30 (47%) больных. Одна-, двух-, трехлетняя безрецидивная выживаемость составила 61 ± 11%, 20 ± 11%, 0%; общая — 95 ± 4%, 74 ± 14%, 37 ± 19%, соответственно. Медиана безрецидивной выживаемости в группе с изолированным поражением забрюшинных лимфоузлов составила 14 (9–29) месяцев, а в группе с метастазами в забрюшинные лимфоузлы в сочетании с синхронным поражением печени — 10 (6–18) месяцев и не имела статистических различий. Одно- и трехлетняя безрецидивная выживаемость была одинаковая в группах и составила 58% ± 15 и 0%, p = 0,2. Унивариантный анализ не выявил факторов, связанных с общей и безрецидивной выживаемостью.</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ: у отобранной группы больных колоректальным раком, с поражением забрюшинных лимфоузлов, в том числе и с резектабельными метастазами в другие органы, хирургическое лечение может быть предпринято, поскольку сопровождается относительно низкой частотой осложнений. Однако малое число наблюдений требует дальнейшего изучения данного вопроса.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>AIM</title><p>AIM: to evaluate the effect of surgery for metastases in retroperitoneal and pelvic lymph nodes on overall and disease-free survival.</p></sec><sec><title>PATIENTS AND METHODS</title><p>PATIENTS AND METHODS: the analysis included 30 patients with retroperitoneal lymph node metastases of colorectal cancer. Synchronous metastases to the retroperitoneal lymph nodes, were diagnosed in 21/30 (70%).</p></sec><sec><title>RESULTS</title><p>RESULTS: the median overall and disease-free survival in patients who underwent lymphodissection was 32 and 13 months, respectively. Recurrence occurred in 14/30 (47%) patients. One-, two-, three-year disease-free survival was 61 ± 11%, 20 ± 11%, 0%; general 95 ± 4%, 74 ± 14%, 37 ± 19%, relatively. The median disease-free survival in the group with isolated retroperitoneal lymph node lesion was 14 (9–29) months and 10 (6–18) months in the group with retroperitoneal lymph node metastases in combination with synchronous liver lesion. One-and three-year disease-free survival was the same in the groups and was 58 ± 15% and 0%, p = 0.2. The univariate analysis did not reveal any factors related to overall and disease-free survival.</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION: in a selected group of patients with colorectal cancer, with lesions of retroperitoneal lymph nodes, including resectable metastases to the other organs, surgery can be justified, since it is accompanied by a relatively low rate of complications. However, the small cohort requires further study.</p></sec><sec><title></title><p>.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рак прямой кишки</kwd><kwd>хирургическое вмешательство</kwd><kwd>колоректальный рак</kwd><kwd>метастазы в лимфатические узлы</kwd><kwd>метастазы в забрюшинные лимфатические узлы</kwd><kwd>метастазы колоректального рака</kwd><kwd>лимфодиссекция</kwd><kwd>метастазы в парааортальные лимфатические узлы</kwd><kwd>лимфаденэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rectal cancer</kwd><kwd>surgery</kwd><kwd>colorectal cancer</kwd><kwd>lymph node metastases</kwd><kwd>retroperitoneal lymph node metastases</kwd><kwd>metastases of colorectal cancer</kwd><kwd>lymphodissection</kwd><kwd>paraaortic lymph node metastases</kwd><kwd>lymphadenectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nordlinger B., et al. 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