<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2022-21-2-10-24</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1726</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Аденоматозный полипозный синдром</article-title><trans-title-group xml:lang="en"><trans-title>Adenomatous polyposis syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шелыгин</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shelygin</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Анатольевич Шелыгин</p></bio><bio xml:lang="en"><p>Yuri A. Shelygin</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Имянитов</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Imyanitov</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Наумович Имянитов</p></bio><bio xml:lang="en"><p>Evgeny N. Imyanitov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куцев</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutsev</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Иванович Куцев</p></bio><bio xml:lang="en"><p>Sergey I. Kutsev</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачкасов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Иванович Ачкасов</p></bio><bio xml:lang="en"><p>Sergey I. Achkasov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasiliev</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Васильевич Васильев</p></bio><bio xml:lang="en"><p>Sergey V. Vasiliev</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Алексеевич Фролов</p></bio><bio xml:lang="en"><p>Sergey A. Frolov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашников</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashnikov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Николаевич Кашников</p></bio><bio xml:lang="en"><p>Vladimir N. Kashnikov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьминов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzminov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Михайлович Кузьминов</p></bio><bio xml:lang="en"><p>Alexander M. Kuzminov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбаков</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakov</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Геннадиевич Рыбаков</p></bio><bio xml:lang="en"><p>Evgeny G. Rybakov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрельников</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Strelnikov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Викторович Стрельников</p></bio><bio xml:lang="en"><p>Vladimir V. Strelnikov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вышегородцев</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyshegorodtsev</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Вячеславович Вышегородцев</p></bio><bio xml:lang="en"><p>Dmitry V. Vyshegorodtsev</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цуканов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsukanov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Сергеевич Цуканов</p></bio><bio xml:lang="en"><p>Alexey S. Tsukanov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москалев</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskalev</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Игоревич Москалев</p></bio><bio xml:lang="en"><p>Alexey I. Moskalev</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пикунов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Pikunov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Юрьевич Пикунов</p><p>Электронный адрес: polikarpova-e@yandex.ru</p></bio><bio xml:lang="en"><p>Dmitry Yu. Pikunov</p></bio><email xlink:type="simple">pikunov.gnck@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ассоциация колопроктологов России; Ассоциация медицинских генетиков</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Association of Coloproctologists of Russia; Association of Medical Geneticists</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>21</day><month>06</month><year>2022</year></pub-date><volume>21</volume><issue>2</issue><fpage>10</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шелыгин Ю.А., Имянитов Е.Н., Куцев С.И., Ачкасов С.И., Васильев С.В., Фролов С.А., Кашников В.Н., Кузьминов А.М., Рыбаков Е.Г., Стрельников В.В., Вышегородцев Д.В., Цуканов А.С., Москалев А.И., Пикунов Д.Ю., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шелыгин Ю.А., Имянитов Е.Н., Куцев С.И., Ачкасов С.И., Васильев С.В., Фролов С.А., Кашников В.Н., Кузьминов А.М., Рыбаков Е.Г., Стрельников В.В., Вышегородцев Д.В., Цуканов А.С., Москалев А.И., Пикунов Д.Ю.</copyright-holder><copyright-holder xml:lang="en">Shelygin Y.A., Imyanitov E.N., Kutsev S.I., Achkasov S.I., Vasiliev S.V., Frolov S.A., Kashnikov V.N., Kuzminov A.M., Rybakov E.G., Strelnikov V.V., Vyshegorodtsev D.V., Tsukanov A.S., Moskalev A.I., Pikunov D.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1726">https://www.ruproctology.com/jour/article/view/1726</self-uri><abstract><p>   Кодирование по D12 Международной статистической классификации болезней и проблем, связанных со здоровьем: Возрастная группа: взрослые.</p></abstract><trans-abstract xml:lang="en"><p>   Coding according to D12 of the International Statistical Classification of Diseases and Health-Related Problems: Age group: adults.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аутосомно-доминантный тип наследования</kwd><kwd>аутосомно-рецессивный тип наследования</kwd><kwd>пробанд</kwd><kwd>родословное древо</kwd><kwd>герминальные (наследственные) мутации</kwd><kwd>аденома</kwd><kwd>полип</kwd><kwd>зубчатая аденома</kwd><kwd>гиперпластический полип</kwd><kwd>десмоидная опухоль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>autosomal dominant type of inheritance</kwd><kwd>autosomal recessive type of inheritance</kwd><kwd>proband</kwd><kwd>family tree</kwd><kwd>hormonal (hereditary) mutations</kwd><kwd>adenoma</kwd><kwd>polyp</kwd><kwd>dentate adenoma</kwd><kwd>hyperplastic polyp</kwd><kwd>desmoid tumor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Справочник по колопроктологии / под редакцией Ю. А. Шелыгина, Л. А. Благодарного. – М.: Литтерра, 2012. – 596 с. / Guide of coloproctology (edited by Yu. A. Shelygin, L. A. Blagodarny). M.: Litterra. 2012; 596 p. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Справочник по колопроктологии / под редакцией Ю. А. Шелыгина, Л. А. Благодарного. – М.: Литтерра, 2012. – 596 с. / Guide of coloproctology (edited by Yu. A. Shelygin, L. A. Blagodarny). M.: Litterra. 2012; 596 p. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Цуканов А. С. Семейный аденоматоз толстой кишки / А. С. Цуканов [и др.] // Хирург. – 2017. – 3: 14–24. / Tsukanov A. S., Shelygin Yu. A., Frolov S. A., Kuzminov A. M. Familial adenomatosis of the colon. Surgeon. 2017; 3: 14–24. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Цуканов А. С. Семейный аденоматоз толстой кишки / А. С. Цуканов [и др.] // Хирург. – 2017. – 3: 14–24. / Tsukanov A. S., Shelygin Yu. A., Frolov S. A., Kuzminov A. M. Familial adenomatosis of the colon. Surgeon. 2017; 3: 14–24. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Groden J., Thliveris A., Samowitz W., et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991; 66: 589–600.</mixed-citation><mixed-citation xml:lang="en">Groden J., Thliveris A., Samowitz W., et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991; 66: 589–600.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Herrera L., Kakati S., Gibas L., et al. Gardner syndrome in man with an interstitial deletion of 5q. Am J Med Genet. 1986; 25: 473–476.</mixed-citation><mixed-citation xml:lang="en">Herrera L., Kakati S., Gibas L., et al. Gardner syndrome in man with an interstitial deletion of 5q. Am J Med Genet. 1986; 25: 473–476.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Joslyn G., Carlson M., Thliveris A., et al. Identification of deletion mutations and three new genes at the familial polyposis locus. Cell. 1991; 66: 601–613.</mixed-citation><mixed-citation xml:lang="en">Joslyn G., Carlson M., Thliveris A., et al. Identification of deletion mutations and three new genes at the familial polyposis locus. Cell. 1991; 66: 601–613.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nallamilli B. R. R., Hegde M. Detecting APC gene mutations in familial adenomatous polyposis (FAP). Curr Protoc Hum Genet. 2017; 92: 10.8.1–10.8.16. DOI: 10.1002/cphg.29</mixed-citation><mixed-citation xml:lang="en">Nallamilli B. R. R., Hegde M. Detecting APC gene mutations in familial adenomatous polyposis (FAP). Curr Protoc Hum Genet. 2017; 92: 10.8.1–10.8.16. DOI: 10.1002/cphg.29</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fodde R. The APC gene in colorectal cancer. Eur J Cancer. 2002; 38 (7): 867–871.</mixed-citation><mixed-citation xml:lang="en">Fodde R. The APC gene in colorectal cancer. Eur J Cancer. 2002; 38 (7): 867–871.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tsukanov A. S., Pospekhova N. I., Shubin V. P., Kuzminov A. M., et al. Mutations in the APC gene in Russian patients with classic form of familial adenomatous polyposis. Russian Journal of Genetics. 2017; 53 (3): 369–375.</mixed-citation><mixed-citation xml:lang="en">Tsukanov A. S., Pospekhova N. I., Shubin V. P., Kuzminov A. M., et al. Mutations in the APC gene in Russian patients with classic form of familial adenomatous polyposis. Russian Journal of Genetics. 2017; 53 (3): 369–375.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kastrinos F., Syngal S. Inherited Colorectal Cancer Syndromes. Cancer J. 2011; 17 (6): 405–415.</mixed-citation><mixed-citation xml:lang="en">Kastrinos F., Syngal S. Inherited Colorectal Cancer Syndromes. Cancer J. 2011; 17 (6): 405–415.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Tassan N., Chmiel N. H., Maynard J., et al. Inherited variants of MYH associated with somatic G:C/T:A mutations in colorectal tumors. Nature Genetics. 2002; 30: 227–232.</mixed-citation><mixed-citation xml:lang="en">Al-Tassan N., Chmiel N. H., Maynard J., et al. Inherited variants of MYH associated with somatic G:C/T:A mutations in colorectal tumors. Nature Genetics. 2002; 30: 227–232.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kantor M., Sobrado J., Patel S., et al. Hereditary Colorectal Tumors: A Literature Review on MutYH-associated Polyposis. Gastroenterology Research and Practice. 2017; 2017: 8693182. DOI: 10.1155/2017/8693182</mixed-citation><mixed-citation xml:lang="en">Kantor M., Sobrado J., Patel S., et al. Hereditary Colorectal Tumors: A Literature Review on MutYH-associated Polyposis. Gastroenterology Research and Practice. 2017; 2017: 8693182. DOI: 10.1155/2017/8693182</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen M., Infante E., Brand R. MutYH Polyposis. In: Adam M. P., Ardinger H. H., Pagon R. A. et al., editors. Gene Reviews® [Internet]. Seattle (WA): University of Washington, Seattle. 2012; 4 [Updated 2019 Oct].</mixed-citation><mixed-citation xml:lang="en">Nielsen M., Infante E., Brand R. MutYH Polyposis. In: Adam M. P., Ardinger H. H., Pagon R. A. et al., editors. Gene Reviews® [Internet]. Seattle (WA): University of Washington, Seattle. 2012; 4 [Updated 2019 Oct].</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Galiatsatos P., Foulkes W. D. Familial adenomatous polyposis. Am J Gastroenterol. 2006; 101 (2): 385–398.</mixed-citation><mixed-citation xml:lang="en">Galiatsatos P., Foulkes W. D. Familial adenomatous polyposis. Am J Gastroenterol. 2006; 101 (2): 385–398.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Septer S., Lawson C. E., Anant S., Attard T. Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate. Fam Cancer. 2016; 15 (3): 477–485.</mixed-citation><mixed-citation xml:lang="en">Septer S., Lawson C. E., Anant S., Attard T. Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate. Fam Cancer. 2016; 15 (3): 477–485.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2018 году (заболеваемость и смертность) / под редакцией А. Д. Каприна, В. В. Старинского, Г. В. Петровой. – М.: МНИОИ им. П. А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России. – 2019. – С. 11–12. / Malignant neoplasms in Russia in 2018 (morbidity and mortality) (edited by A. D. Kaprin, V. V. Starinsky, G. V. Petrova). Moscow: P. A. Herzen Institute of Medical Research — Branch of the Federal State Budgetary Institution «NMIC of Radiology» of the Ministry of Health of Russia. 2019; pp. 11–12. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Злокачественные новообразования в России в 2018 году (заболеваемость и смертность) / под редакцией А. Д. Каприна, В. В. Старинского, Г. В. Петровой. – М.: МНИОИ им. П. А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России. – 2019. – С. 11–12. / Malignant neoplasms in Russia in 2018 (morbidity and mortality) (edited by A. D. Kaprin, V. V. Starinsky, G. V. Petrova). Moscow: P. A. Herzen Institute of Medical Research — Branch of the Federal State Budgetary Institution «NMIC of Radiology» of the Ministry of Health of Russia. 2019; pp. 11–12. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Цуканов А. С. Наследственные раки желудочно-кишечного тракта / А. С. Цуканов [и др.] // Практическая онкология. – 2014. – 15 (3): 126–133. / Tsukanov A. S., Shubin V. P., Pospekhova N. I., Sachkov I. Yu. et al. Hereditary cancers of the gastrointestinal tract. Practical oncology. 2014; 15 (3): 126–133. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Цуканов А. С. Наследственные раки желудочно-кишечного тракта / А. С. Цуканов [и др.] // Практическая онкология. – 2014. – 15 (3): 126–133. / Tsukanov A. S., Shubin V. P., Pospekhova N. I., Sachkov I. Yu. et al. Hereditary cancers of the gastrointestinal tract. Practical oncology. 2014; 15 (3): 126–133. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Rozen P/, Macrae F. Familial adenomatous polyposis: The practical applications of clinical and molecular screening. Fam Cancer. 2006; 5: 227–235.</mixed-citation><mixed-citation xml:lang="en">Rozen P/, Macrae F. Familial adenomatous polyposis: The practical applications of clinical and molecular screening. Fam Cancer. 2006; 5: 227–235.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Цуканов А. С. Дифференциальный диагноз синдрома Линча от других форм неполипозного колоректального рака среди российских пациентов / А. С. Цуканов [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2014. – 24 (2): 78–84. / Tsukanov A. S., Pospekhova N. I., Shubin V. P., et al. Differential diagnosis of Lynch syndrome from other forms of non-polypous colorectal cancer among Russian patients. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2014; 24 (2): 78–84. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Цуканов А. С. Дифференциальный диагноз синдрома Линча от других форм неполипозного колоректального рака среди российских пациентов / А. С. Цуканов [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2014. – 24 (2): 78–84. / Tsukanov A. S., Pospekhova N. I., Shubin V. P., et al. Differential diagnosis of Lynch syndrome from other forms of non-polypous colorectal cancer among Russian patients. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2014; 24 (2): 78–84. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Grover S., Kastrinos F., Steyerberg E. W., et al. Prevalence and phenotypes of APC and MutYH mutations in patients with multiple colorectal adenomas. JAMA. 2012; 308: 485–492.</mixed-citation><mixed-citation xml:lang="en">Grover S., Kastrinos F., Steyerberg E. W., et al. Prevalence and phenotypes of APC and MutYH mutations in patients with multiple colorectal adenomas. JAMA. 2012; 308: 485–492.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Scheuner M., McNeel T., Freedman A. Population prevalence of familial cancer and common hereditary cancer syndromes. The 2005 California Health Interview Survey. Genet Med. 2010; 12: 726–735.</mixed-citation><mixed-citation xml:lang="en">Scheuner M., McNeel T., Freedman A. Population prevalence of familial cancer and common hereditary cancer syndromes. The 2005 California Health Interview Survey. Genet Med. 2010; 12: 726–735.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Цуканов А. С. Дифференциальный диагноз MutYH-ассоциированного полипоза и спорадических полипов толстой кишки / А. С. Цуканов [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2018. – 28 (6): 51–57 / Tsukanov A. S., Shubin V. P., Kuzminov A. M. et al. Differential diagnosis of MutYH-associated polyposis and sporadic colon polyps. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2018; 28 (6): 51–57. (In Russ.). DOI: 10.22416/1382-4376-2018-28-6-51-57</mixed-citation><mixed-citation xml:lang="en">Цуканов А. С. Дифференциальный диагноз MutYH-ассоциированного полипоза и спорадических полипов толстой кишки / А. С. Цуканов [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2018. – 28 (6): 51–57 / Tsukanov A. S., Shubin V. P., Kuzminov A. M. et al. Differential diagnosis of MutYH-associated polyposis and sporadic colon polyps. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2018; 28 (6): 51–57. (In Russ.). DOI: 10.22416/1382-4376-2018-28-6-51-57</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Grover S., Kastrinos F., Steyerberg E. W. et al. Prevalence and Phenotypes of APC and MutYH Mutations in Patients with Multiple Colorectal Adenomas. JAMA. 2012; 308 (5): 485–492.</mixed-citation><mixed-citation xml:lang="en">Grover S., Kastrinos F., Steyerberg E. W. et al. Prevalence and Phenotypes of APC and MutYH Mutations in Patients with Multiple Colorectal Adenomas. JAMA. 2012; 308 (5): 485–492.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Dinarvand P., Davaro E. P., Doan J. V. et al. Familial Adenomatous Polyposis Syndrome: An Update and Review of Extraintestinal Manifestations. Arch Pathol Lab Med. 2019; 143 (11): 1382–1398.</mixed-citation><mixed-citation xml:lang="en">Dinarvand P., Davaro E. P., Doan J. V. et al. Familial Adenomatous Polyposis Syndrome: An Update and Review of Extraintestinal Manifestations. Arch Pathol Lab Med. 2019; 143 (11): 1382–1398.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Brensinger J. D., Laken S. J., Luce M. C., et al. Variable phenotype of familial adenomatous polyposis in pedigrees with 3’ mutation in the APC gene. Gut. 1998; 43 (4): 548–552.</mixed-citation><mixed-citation xml:lang="en">Brensinger J. D., Laken S. J., Luce M. C., et al. Variable phenotype of familial adenomatous polyposis in pedigrees with 3’ mutation in the APC gene. Gut. 1998; 43 (4): 548–552.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Soravia C., Berk T., Madlensky L., et al. Genotype-phenotype correlations in attenuated adenomatous polyposis coli. Am J Hum Genet. 1998; 62: 1290–1301.</mixed-citation><mixed-citation xml:lang="en">Soravia C., Berk T., Madlensky L., et al. Genotype-phenotype correlations in attenuated adenomatous polyposis coli. Am J Hum Genet. 1998; 62: 1290–1301.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Lal G., Gallinger S. Familial adenomatous polyposis. Seminars in Surgical Oncology. 2000; 18: 314–323.</mixed-citation><mixed-citation xml:lang="en">Lal G., Gallinger S. Familial adenomatous polyposis. Seminars in Surgical Oncology. 2000; 18: 314–323.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Novelli M. The pathology of hereditary polyposis syndromes. Histopathology. 2015; 66 (1): 78–87.</mixed-citation><mixed-citation xml:lang="en">Novelli M. The pathology of hereditary polyposis syndromes. Histopathology. 2015; 66 (1): 78–87.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Barrow P., Khan M., Lalloo F., Evans D. G., et al. Systematic review of the impact of registration and screening on colorectal cancer incidence and mortality in familial adenomatous polyposis and Lynch syndrome. Br J Surg. 2013; 100: 1719–1731.</mixed-citation><mixed-citation xml:lang="en">Barrow P., Khan M., Lalloo F., Evans D. G., et al. Systematic review of the impact of registration and screening on colorectal cancer incidence and mortality in familial adenomatous polyposis and Lynch syndrome. Br J Surg. 2013; 100: 1719–1731.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Riley B. D., Culver J. O., Skrzynia C., et al. Essential elements of genetic cancer risk assessment, counseling, and testing: updated recommendations of the National Society of Genetic Counselors. J Genet Couns. 2012; 21: 151–161.</mixed-citation><mixed-citation xml:lang="en">Riley B. D., Culver J. O., Skrzynia C., et al. Essential elements of genetic cancer risk assessment, counseling, and testing: updated recommendations of the National Society of Genetic Counselors. J Genet Couns. 2012; 21: 151–161.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Brensinger J. D., Laken S. J., Luce M. C., et al. Variable phenotype of familial adenomatous polyposis in pedigrees with 3’ mutation in the APC gene. Gut. 1998; 43 (4): 548–552.</mixed-citation><mixed-citation xml:lang="en">Brensinger J. D., Laken S. J., Luce M. C., et al. Variable phenotype of familial adenomatous polyposis in pedigrees with 3’ mutation in the APC gene. Gut. 1998; 43 (4): 548–552.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Talseth-Palmer B. A. The genetic basis of colonic adenomatouspolyposis syndromes. Hereditary Cancer in Clinical Practice. 2017; 15: 5. DOI: 10.1186/s13053-017-0065-x</mixed-citation><mixed-citation xml:lang="en">Talseth-Palmer B. A. The genetic basis of colonic adenomatouspolyposis syndromes. Hereditary Cancer in Clinical Practice. 2017; 15: 5. DOI: 10.1186/s13053-017-0065-x</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J. R. Colorectal polyposes: from phenotype to diagnosis. Pathol Res Pract. 2008; 204 (7): 431–47.</mixed-citation><mixed-citation xml:lang="en">Jass J. R. Colorectal polyposes: from phenotype to diagnosis. Pathol Res Pract. 2008; 204 (7): 431–47.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Friedl W., Caspari R., Sengteller M., et al. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families. Gut. 2001; 48: 515–521.</mixed-citation><mixed-citation xml:lang="en">Friedl W., Caspari R., Sengteller M., et al. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families. Gut. 2001; 48: 515–521.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Цуканов А. С. Стратегия комплексного молекулярно-генетического изучения наследственных форм колоректального рака у российских пациентов: автореф. … д-ра. мед. наук / А. С. Цуканов. – Москва, 2017. – 48 с. / Tsukanov A. S. Strategy of complex molecular genetic study of hereditary forms of colorectal cancer in Russian patients (abstract. … doctor of medical sciences). Moscow. 2017; 48 р. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Цуканов А. С. Стратегия комплексного молекулярно-генетического изучения наследственных форм колоректального рака у российских пациентов: автореф. … д-ра. мед. наук / А. С. Цуканов. – Москва, 2017. – 48 с. / Tsukanov A. S. Strategy of complex molecular genetic study of hereditary forms of colorectal cancer in Russian patients (abstract. … doctor of medical sciences). Moscow. 2017; 48 р. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Herzig D., Hardiman K., Weiser M., et al. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Inherited Polyposis Syndromes. Dis Colon Rectum. 2017; 60 (9): 881–894.</mixed-citation><mixed-citation xml:lang="en">Herzig D., Hardiman K., Weiser M., et al. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Inherited Polyposis Syndromes. Dis Colon Rectum. 2017; 60 (9): 881–894.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Syngal S., Brand R. E., Church J. M., et al. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015; 110 (2): 223–263.</mixed-citation><mixed-citation xml:lang="en">Syngal S., Brand R. E., Church J. M., et al. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015; 110 (2): 223–263.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Groves C. J., Saunders B. P., Spigelman A. D., Phillips R. K. Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10-year prospective study. Gut. 2002; 50: 636–634.</mixed-citation><mixed-citation xml:lang="en">Groves C. J., Saunders B. P., Spigelman A. D., Phillips R. K. Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10-year prospective study. Gut. 2002; 50: 636–634.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Spigelman A., Talbot I., Williams C., et al. Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 1989; 334 (8666): 783–785.</mixed-citation><mixed-citation xml:lang="en">Spigelman A., Talbot I., Williams C., et al. Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 1989; 334 (8666): 783–785.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Brosens L. A., Keller J. J., Offerhaus G. J. A., et al. Prevention and management of duodenal polyps in familial adenomatous polyposis. Gut. 2005; 54 (7): 1034–1043.</mixed-citation><mixed-citation xml:lang="en">Brosens L. A., Keller J. J., Offerhaus G. J. A., et al. Prevention and management of duodenal polyps in familial adenomatous polyposis. Gut. 2005; 54 (7): 1034–1043.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Leone P. J., Mankaney G., Sarvapelli Sh., et al. Endoscopic and histologic features associated with gastric cancer in familial adenomatous polyposis. Gastrointest Endosc. 2019; 89 (5): 961–968.</mixed-citation><mixed-citation xml:lang="en">Leone P. J., Mankaney G., Sarvapelli Sh., et al. Endoscopic and histologic features associated with gastric cancer in familial adenomatous polyposis. Gastrointest Endosc. 2019; 89 (5): 961–968.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Kallenberg F. G. J., Bastiaansen B. A. J., Dekker E., Capassisted forward-viewing endoscopy to visualize the ampulla of Vater and the duodenum in patients with familial adenomatous polyposis. Endoscopy. 2017; 49 (2): 181–185.</mixed-citation><mixed-citation xml:lang="en">Kallenberg F. G. J., Bastiaansen B. A. J., Dekker E., Capassisted forward-viewing endoscopy to visualize the ampulla of Vater and the duodenum in patients with familial adenomatous polyposis. Endoscopy. 2017; 49 (2): 181–185.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">de Marchis M. L., Tonelli F., Quaresmini D., et al. Desmoid Tumors in Familial Adenomatous Polyposis. Anticancer Res. 2017; 37 (7): 3357–3366.</mixed-citation><mixed-citation xml:lang="en">de Marchis M. L., Tonelli F., Quaresmini D., et al. Desmoid Tumors in Familial Adenomatous Polyposis. Anticancer Res. 2017; 37 (7): 3357–3366.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Campos F. G., Martinez C. A., Novaes M., Nahas S. C. Desmoid tumors: clinical features and outcome of an unpredictable and challenging manifestation of familial adenomatous polyposis. Fam Cancer. 2015; 14 (2): 211–219.</mixed-citation><mixed-citation xml:lang="en">Campos F. G., Martinez C. A., Novaes M., Nahas S. C. Desmoid tumors: clinical features and outcome of an unpredictable and challenging manifestation of familial adenomatous polyposis. Fam Cancer. 2015; 14 (2): 211–219.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Будтуев А. С. Синдром низкой передней резекции прямой кишки и методы его хирургической коррекции / А. С. Будтуев [и др.] // Вестник хирургии им. И. И. Грекова. – 2014. – 173 (4): 106–110. / Budtuev A. S., Pikunov D. Yu., Rybakov E. G., Sevostyanov S. I. Low anterior rectal resection syndrome and methods of its surgical correction. Bulletin of Surgery named after I. I. Grekov. 2014; 173 (4): 106–110. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Будтуев А. С. Синдром низкой передней резекции прямой кишки и методы его хирургической коррекции / А. С. Будтуев [и др.] // Вестник хирургии им. И. И. Грекова. – 2014. – 173 (4): 106–110. / Budtuev A. S., Pikunov D. Yu., Rybakov E. G., Sevostyanov S. I. Low anterior rectal resection syndrome and methods of its surgical correction. Bulletin of Surgery named after I. I. Grekov. 2014; 173 (4): 106–110. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Подберезская А. А. Современные хирургические методы лечения полипоза толстой кишки / А. А. Подберезская [и др.] // Журнал Гродненского государственного медицинского университета. – 2016. – 4 (56): 26–29. / Podberezskaya A. A., Salmin R. M., Mogilevets E. V., et al. Modern surgical methods of treatment of colon polyposis. Journal of Grodno State Medical University. 2016; 4 (56): 26–29. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Подберезская А. А. Современные хирургические методы лечения полипоза толстой кишки / А. А. Подберезская [и др.] // Журнал Гродненского государственного медицинского университета. – 2016. – 4 (56): 26–29. / Podberezskaya A. A., Salmin R. M., Mogilevets E. V., et al. Modern surgical methods of treatment of colon polyposis. Journal of Grodno State Medical University. 2016; 4 (56): 26–29. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Фоменко О. Ю. Современные возможности улучшения функционального состояния запирательного аппарата у пациентов с наличием превентивных кишечных стом / О. Ю. Фоменко [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2015. – 25 (5): 77–83. / Fomenko O. Yu., Achkasov S. I., Titov A. Yu. et al. Modern possibilities of improving the functional state of the locking device in patients with the presence of preventive intestinal stomas. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2015; 25 (5): 77–83. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Фоменко О. Ю. Современные возможности улучшения функционального состояния запирательного аппарата у пациентов с наличием превентивных кишечных стом / О. Ю. Фоменко [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2015. – 25 (5): 77–83. / Fomenko O. Yu., Achkasov S. I., Titov A. Yu. et al. Modern possibilities of improving the functional state of the locking device in patients with the presence of preventive intestinal stomas. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2015; 25 (5): 77–83. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Roncucci L., Pedroni M., Mariani F. Attenuated adenomatous polyposis of the large bowel: Present and future. World J Gastroenterol. 2017; 23 (23): 4135–4139.</mixed-citation><mixed-citation xml:lang="en">Roncucci L., Pedroni M., Mariani F. Attenuated adenomatous polyposis of the large bowel: Present and future. World J Gastroenterol. 2017; 23 (23): 4135–4139.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Burns E. M., Bottle A., Aylin P., et al. Volume analysis of outcome following restorative proctocolectomy. Br J Surg. 2011; 98: 408–417.</mixed-citation><mixed-citation xml:lang="en">Burns E. M., Bottle A., Aylin P., et al. Volume analysis of outcome following restorative proctocolectomy. Br J Surg. 2011; 98: 408–417.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Sylla P., Chessin D. B., Gorfine S. R. et al. Evaluation of onestage laparoscopic-assisted restorative proctocolectomy at a specialty center: comparison with the open approach. Dis Colon Rectum. 2009; 52 (3): 394–399.</mixed-citation><mixed-citation xml:lang="en">Sylla P., Chessin D. B., Gorfine S. R. et al. Evaluation of onestage laparoscopic-assisted restorative proctocolectomy at a specialty center: comparison with the open approach. Dis Colon Rectum. 2009; 52 (3): 394–399.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang H., Hu S., Zhang G., et al. Laparoscopic versus open proctocolectomy with ileal pouch-anal anastomosis. Minim Invasive Ther Allied Technol. 2007; 16 (3): 187–191.</mixed-citation><mixed-citation xml:lang="en">Zhang H., Hu S., Zhang G., et al. Laparoscopic versus open proctocolectomy with ileal pouch-anal anastomosis. Minim Invasive Ther Allied Technol. 2007; 16 (3): 187–191.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Norenberg D., Sommer W. H., Thasler W., et al. Structured Reporting of Rectal Magnetic Resonance Imaging in Suspected Primary Rectal Cancer: Potential Benefits for Surgical Planning and Interdisciplinary Communication. Invest Radiol. 2017; 52 (4): 232–239.</mixed-citation><mixed-citation xml:lang="en">Norenberg D., Sommer W. H., Thasler W., et al. Structured Reporting of Rectal Magnetic Resonance Imaging in Suspected Primary Rectal Cancer: Potential Benefits for Surgical Planning and Interdisciplinary Communication. Invest Radiol. 2017; 52 (4): 232–239.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Ellis C. N. Colonic adenomatous polyposis syndromes: clinical management. Clin Colon Rectal Surg. 2008; 21: 256–262.</mixed-citation><mixed-citation xml:lang="en">Ellis C. N. Colonic adenomatous polyposis syndromes: clinical management. Clin Colon Rectal Surg. 2008; 21: 256–262.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Aziz O., Athanasiou T., Fazio V. W., et al. Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis. Br J Surg. 2006; 93: 407–417.</mixed-citation><mixed-citation xml:lang="en">Aziz O., Athanasiou T., Fazio V. W., et al. Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis. Br J Surg. 2006; 93: 407–417.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Tajika M., Niwa Y., Bhatia V., et al. Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis. World J Gastroenterol. 2013; 19: 6774–6783.</mixed-citation><mixed-citation xml:lang="en">Tajika M., Niwa Y., Bhatia V., et al. Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis. World J Gastroenterol. 2013; 19: 6774–6783.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Lynch Р. М., Morris J. S., Wen S., et al. Proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointest Endosc. 2016; 84 (1): 115–125.</mixed-citation><mixed-citation xml:lang="en">Lynch Р. М., Morris J. S., Wen S., et al. Proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointest Endosc. 2016; 84 (1): 115–125.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Knudsen A., Bisgaard M., Bulow S. Attenuated familial adenomatous polyposis (AFAP). A review of the literature. Fam Cancer. 2003; 2: 43–55.</mixed-citation><mixed-citation xml:lang="en">Knudsen A., Bisgaard M., Bulow S. Attenuated familial adenomatous polyposis (AFAP). A review of the literature. Fam Cancer. 2003; 2: 43–55.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Nascimbeni R., Pucciarelli S., Di Lorenzo D., et al. Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis. Dis Colon Rectum. 2010; 53: 1670–1675.</mixed-citation><mixed-citation xml:lang="en">Nascimbeni R., Pucciarelli S., Di Lorenzo D., et al. Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis. Dis Colon Rectum. 2010; 53: 1670–1675.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации «Злокачественные новообразования ободочной кишки и ректосигмоидного отдела», год утверждения: 2020. http://cr.rosminzdrav.ru/recomend/396 1 / Clinical recommendations “Malignant neoplasms of the colon and rectosigmoid department”, 2020. http://cr.rosminzdrav.ru/recomend/396 1. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Клинические рекомендации «Злокачественные новообразования ободочной кишки и ректосигмоидного отдела», год утверждения: 2020. http://cr.rosminzdrav.ru/recomend/396 1 / Clinical recommendations “Malignant neoplasms of the colon and rectosigmoid department”, 2020. http://cr.rosminzdrav.ru/recomend/396 1. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации «Рак прямой кишки», год утверждения: 2020. http://cr.rosminzdrav.ru/recomend/554_2. / Clinical recommendations “Rectal cancer”, 2020. http://cr.rosminzdrav.ru/recomend/554_2. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Клинические рекомендации «Рак прямой кишки», год утверждения: 2020. http://cr.rosminzdrav.ru/recomend/554_2. / Clinical recommendations “Rectal cancer”, 2020. http://cr.rosminzdrav.ru/recomend/554_2. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Nieuwenhuis M. H., Lefevre J. H., Bulow S., et al. Family history, surgery, and APC mutation are risk factors for desmoid tumors in familial adenomatous polyposis: an international cohort study. Dis Colon Rectum. 2011; 54: 1229–1234.</mixed-citation><mixed-citation xml:lang="en">Nieuwenhuis M. H., Lefevre J. H., Bulow S., et al. Family history, surgery, and APC mutation are risk factors for desmoid tumors in familial adenomatous polyposis: an international cohort study. Dis Colon Rectum. 2011; 54: 1229–1234.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Speake D., Evans D. G., Lalloo F., et al. Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg. 2007; 94: 1009–1013.</mixed-citation><mixed-citation xml:lang="en">Speake D., Evans D. G., Lalloo F., et al. Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg. 2007; 94: 1009–1013.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Quast D. R., Schneider R., Burdzik E., et al. Long-term outcome of sporadic and FAP-associated desmoid tumors treated with high-dose selective estrogen receptor modulators and sulindac: a single-center long-term observational study in 134 patients. Fam Cancer. 2016; 15: 31–40.</mixed-citation><mixed-citation xml:lang="en">Quast D. R., Schneider R., Burdzik E., et al. Long-term outcome of sporadic and FAP-associated desmoid tumors treated with high-dose selective estrogen receptor modulators and sulindac: a single-center long-term observational study in 134 patients. Fam Cancer. 2016; 15: 31–40.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации «Кишечная стома у взрослых». – 2017. http://akr-online.ru/press/clinical-guidelines/recommendationstoma.pdf. / Clinical recommendations “Intestinal stoma in adults”. 2017. http://akr-online.ru/press/clinical-guidelines/recommendationstoma.pdf. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Клинические рекомендации «Кишечная стома у взрослых». – 2017. http://akr-online.ru/press/clinical-guidelines/recommendationstoma.pdf. / Clinical recommendations “Intestinal stoma in adults”. 2017. http://akr-online.ru/press/clinical-guidelines/recommendationstoma.pdf. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Annibali R., Oresland T., Hulten L. Does the level of stapled ileo-anal anastomosis influence physiologic and functional outcome? Dis Colon Rectum. 1994; 37: 321–329.</mixed-citation><mixed-citation xml:lang="en">Annibali R., Oresland T., Hulten L. Does the level of stapled ileo-anal anastomosis influence physiologic and functional outcome? Dis Colon Rectum. 1994; 37: 321–329.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Фоменко О. Ю. Роль аноректальной манометрии, БОС-терапии и тибиальной нейромодуляции в диагностике и консервативном лечении анальной инконтиненции у пожилых / О. Ю. Фоменко [и др.] // Клиническая геронтология. – 2015. –5 (6): 16–20. / Fomenko O. Yu., Achkasov S. I., Titov A. Yu. et al. The role of anorectal manometry, BOS therapy and tibial neuromodulation in the diagnosis and conservative treatment of anal incontinence in the elderly. Clinical gerontology. 2015; 5 (6): 16–20. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Фоменко О. Ю. Роль аноректальной манометрии, БОС-терапии и тибиальной нейромодуляции в диагностике и консервативном лечении анальной инконтиненции у пожилых / О. Ю. Фоменко [и др.] // Клиническая геронтология. – 2015. –5 (6): 16–20. / Fomenko O. Yu., Achkasov S. I., Titov A. Yu. et al. The role of anorectal manometry, BOS therapy and tibial neuromodulation in the diagnosis and conservative treatment of anal incontinence in the elderly. Clinical gerontology. 2015; 5 (6): 16–20. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Labayle D., Fischer D., Vielh P., et al. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology. 1991; 101: 635–639.</mixed-citation><mixed-citation xml:lang="en">Labayle D., Fischer D., Vielh P., et al. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology. 1991; 101: 635–639.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Steinbach G., Lynch P. M., Phillips R. K. S., et al. The effect of celecoxib, a cyclooxygenase- 2 inhibitor, in familial adenomatous polyposis. N Engl J Med. 2000; 342: 1946–1952.</mixed-citation><mixed-citation xml:lang="en">Steinbach G., Lynch P. M., Phillips R. K. S., et al. The effect of celecoxib, a cyclooxygenase- 2 inhibitor, in familial adenomatous polyposis. N Engl J Med. 2000; 342: 1946–1952.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Nugent K. P., Farmer K. C., Spigelman A. D., et al. Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. Br J Surg. 1993; 80: 1618–1619.</mixed-citation><mixed-citation xml:lang="en">Nugent K. P., Farmer K. C., Spigelman A. D., et al. Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. Br J Surg. 1993; 80: 1618–1619.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Higuchi T., Iwama T., Yoshinaga K., et al. A randomized, doubleblind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin Cancer Res. 2003; 9: 4756–4760.</mixed-citation><mixed-citation xml:lang="en">Higuchi T., Iwama T., Yoshinaga K., et al. A randomized, doubleblind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin Cancer Res. 2003; 9: 4756–4760.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Tonelli F., Valanzano R., Messerini L. et al. Long-term treatment with sulindac in familial adenomatous polyposis: is there an actual efficacy in prevention of rectal cancer? J Surg Oncol. 2000; 74: 15–20.</mixed-citation><mixed-citation xml:lang="en">Tonelli F., Valanzano R., Messerini L. et al. Long-term treatment with sulindac in familial adenomatous polyposis: is there an actual efficacy in prevention of rectal cancer? J Surg Oncol. 2000; 74: 15–20.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Cruz-Correa M., Hylind L. M., Romans K. E., et al. Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Gastroenterology. 2002; 122: 641–645.</mixed-citation><mixed-citation xml:lang="en">Cruz-Correa M., Hylind L. M., Romans K. E., et al. Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Gastroenterology. 2002; 122: 641–645.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">International Society for Gastrointestinal Hereditary Tumours-InSiGHT. Fam Cancer. 2015; 14 (Suppl 1): 1–91.</mixed-citation><mixed-citation xml:lang="en">International Society for Gastrointestinal Hereditary Tumours-InSiGHT. Fam Cancer. 2015; 14 (Suppl 1): 1–91.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Bianchi L. K., Burke C. A., Bennett A. E., et al. Fundic gland polypdysplasia is common in familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008; 6: 180–185.</mixed-citation><mixed-citation xml:lang="en">Bianchi L. K., Burke C. A., Bennett A. E., et al. Fundic gland polypdysplasia is common in familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008; 6: 180–185.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Walton S.-J., Frayling I. M., Clark S. K., et al. Gastric tumours in FAP. Fam Cancer. 2017; 16: 363–369.</mixed-citation><mixed-citation xml:lang="en">Walton S.-J., Frayling I. M., Clark S. K., et al. Gastric tumours in FAP. Fam Cancer. 2017; 16: 363–369.</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Vasen H. F., Bulow S., Myrhoj T., et al. Decision analysis in the management of duodenal adenomatosis in familial adenomatous polyposis. Gut. 1997; 40: 716–719.</mixed-citation><mixed-citation xml:lang="en">Vasen H. F., Bulow S., Myrhoj T., et al. Decision analysis in the management of duodenal adenomatosis in familial adenomatous polyposis. Gut. 1997; 40: 716–719.</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Bulow S., Christensen I. J., Hojen H., et al. Duodenal surveillance improves the prognosis after duodenal cancer in familial adenomatous polyposis. Colorectal Dis. 2012; 14: 947–952.</mixed-citation><mixed-citation xml:lang="en">Bulow S., Christensen I. J., Hojen H., et al. Duodenal surveillance improves the prognosis after duodenal cancer in familial adenomatous polyposis. Colorectal Dis. 2012; 14: 947–952.</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Spigelman A. D., Williams C. B., Talbot I. C., et al. Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 1989; 2: 783–785.</mixed-citation><mixed-citation xml:lang="en">Spigelman A. D., Williams C. B., Talbot I. C., et al. Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 1989; 2: 783–785.</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Groves C. J., Saunders B. P., Spigelman A. D., et al. Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10-year prospective study. Gut. 2002; 50: 636–641.</mixed-citation><mixed-citation xml:lang="en">Groves C. J., Saunders B. P., Spigelman A. D., et al. Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10-year prospective study. Gut. 2002; 50: 636–641.</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Shepherd N. A., Jass J.R., Duval I., et al. Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol. 1987; 40: 601–607.</mixed-citation><mixed-citation xml:lang="en">Shepherd N. A., Jass J.R., Duval I., et al. Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol. 1987; 40: 601–607.</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Setti Carraro P. G., Talbot I. C., Nicholls J. R. Patterns of distribution of endoscopic and histological changes in the ileal reservoir after restorative proctocolectomy for ulcerative colitis. A long-term follow-up study. Int J Colorectal Dis. 1998; 13: 103–107.</mixed-citation><mixed-citation xml:lang="en">Setti Carraro P. G., Talbot I. C., Nicholls J. R. Patterns of distribution of endoscopic and histological changes in the ileal reservoir after restorative proctocolectomy for ulcerative colitis. A long-term follow-up study. Int J Colorectal Dis. 1998; 13: 103–107.</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Friederich P., de Jong A. E., Mathus-Vliegen L. M., et al. Risk of developing adenomas and carcinomas in the ileal pouch in patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008; 6: 1237–1642.</mixed-citation><mixed-citation xml:lang="en">Friederich P., de Jong A. E., Mathus-Vliegen L. M., et al. Risk of developing adenomas and carcinomas in the ileal pouch in patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008; 6: 1237–1642.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Speake D., Evans D. G., Lalloo F., et al. Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg. 2007; 94: 1009–1013.</mixed-citation><mixed-citation xml:lang="en">Speake D., Evans D. G., Lalloo F., et al. Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg. 2007; 94: 1009–1013.</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Ahmed Ali U., Keus F., Heikens J. T., et al. Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis. Cochrane Database Syst Rev. 2009 Jan 21; (1): CD006267.</mixed-citation><mixed-citation xml:lang="en">Ahmed Ali U., Keus F., Heikens J. T., et al. Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis. Cochrane Database Syst Rev. 2009 Jan 21; (1): CD006267.</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Ueno H., Kobayashi H., Konishi T., et al. Prevalence of laparoscopic surgical treatment and its clinical outcomes in patients with familial adenomatous polyposis in Japan. Int J Clin Oncol. 2016; 21 (4): 713–722.</mixed-citation><mixed-citation xml:lang="en">Ueno H., Kobayashi H., Konishi T., et al. Prevalence of laparoscopic surgical treatment and its clinical outcomes in patients with familial adenomatous polyposis in Japan. Int J Clin Oncol. 2016; 21 (4): 713–722.</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Fazio V. W., Ziv Y., Church J. M., et al. Ileal pouch-anal anastomoses complications and function in 1005 patients. Ann Surg. 1995; 222: 120–127.</mixed-citation><mixed-citation xml:lang="en">Fazio V. W., Ziv Y., Church J. M., et al. Ileal pouch-anal anastomoses complications and function in 1005 patients. Ann Surg. 1995; 222: 120–127.</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Vasen H. F., van Duijvendijk P., Buskens E., et al. Decision analysis in the surgical treatment of patients with familial adenomatous polyposis: a Dutch-Scandinavian collaborative study including 659 patients. Gut. 2001; 49 (2): 231–5.</mixed-citation><mixed-citation xml:lang="en">Vasen H. F., van Duijvendijk P., Buskens E., et al. Decision analysis in the surgical treatment of patients with familial adenomatous polyposis: a Dutch-Scandinavian collaborative study including 659 patients. Gut. 2001; 49 (2): 231–5.</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">NCCN Clinical Practice Guidelines in Oncology Genetic / Familial High-Risk Assessment: Colorectal version 1.2021.</mixed-citation><mixed-citation xml:lang="en">NCCN Clinical Practice Guidelines in Oncology Genetic / Familial High-Risk Assessment: Colorectal version 1.2021.</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Vasen H. F., Möslein G., Alonso A., Aretz S., et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut. 2008; 57 (5): 704–13.</mixed-citation><mixed-citation xml:lang="en">Vasen H. F., Möslein G., Alonso A., Aretz S., et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut. 2008; 57 (5): 704–13.</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Aelvoet A. S., Struik D., Bastiaansen B. A. J., et al. Colectomy and desmoid tumours in familial adenomatous polyposis: a systematic review and meta-analysis. Familial Cancer. (2022), DOI: 10.1007/s10689-022-00288-y</mixed-citation><mixed-citation xml:lang="en">Aelvoet A. S., Struik D., Bastiaansen B. A. J., et al. Colectomy and desmoid tumours in familial adenomatous polyposis: a systematic review and meta-analysis. Familial Cancer. (2022), DOI: 10.1007/s10689-022-00288-y</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Jannasch O., Evert M., Rapp L., Lippert H., Meyer F. Aktuelle Diagnostik und Therapie von Desmoidtumorenbei Patienten mit familiärer adenomatöser Polyposis — auschirurgischer Sicht [Current diagnosis and treatment of desmoid tumours in patients with familial adenomatous polyposis — the surgical view]. Zentralbl Chir. German. 2010; 135 (1): 34–43. DOI: 10.1055/s-0028-1098794</mixed-citation><mixed-citation xml:lang="en">Jannasch O., Evert M., Rapp L., Lippert H., Meyer F. Aktuelle Diagnostik und Therapie von Desmoidtumorenbei Patienten mit familiärer adenomatöser Polyposis — auschirurgischer Sicht [Current diagnosis and treatment of desmoid tumours in patients with familial adenomatous polyposis — the surgical view]. Zentralbl Chir. German. 2010; 135 (1): 34–43. DOI: 10.1055/s-0028-1098794</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
