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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2022-21-1-10-25</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1706</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Синдром раздраженного кишечника</article-title><trans-title-group xml:lang="en"><trans-title>Irritable bowel syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. T.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шелыгин</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shelygin</surname><given-names>Y. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранская</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranskaya</surname><given-names>E. K.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачкасов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasov</surname><given-names>S. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоус</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belous</surname><given-names>S. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousova</surname><given-names>E. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бениашвиили</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Beniashviili</surname><given-names>A. G.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasiliev</surname><given-names>S. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoriev</surname><given-names>E. G.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костенко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostenko</surname><given-names>N. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москалев</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskalev</surname><given-names>A. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашников</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashnikov</surname><given-names>V. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лоранская</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Loranskaya</surname><given-names>I. D.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляшенко</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyashenko</surname><given-names>O. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полуэктова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Poluektova</surname><given-names>E. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>V. G.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>V. M.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чашкова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chashkova</surname><given-names>E. Y.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шапина</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shapina</surname><given-names>M. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>A. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шифрин</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shifrin</surname><given-names>O. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зольникова</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zolnikova</surname><given-names>O. Y.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барановский</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranovsky</surname><given-names>A. Y.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корочанская</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korochanskaya</surname><given-names>N. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маммаев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mammaev</surname><given-names>S. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>O. P.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлынов</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khlynov</surname><given-names>I. B.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цуканов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsukanov</surname><given-names>V. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseenko</surname><given-names>S. A.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>17</day><month>03</month><year>2022</year></pub-date><volume>21</volume><issue>1</issue><fpage>10</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ивашкин В.Т., Шелыгин Ю.А., Баранская Е.К., Ачкасов С.И., Белоус С.С., Белоусова Е.А., Бениашвиили А.Г., Васильев С.В., Григорьев Е.Г., Костенко Н.В., Москалев А.И., Кашников В.Н., Лоранская И.Д., Ляшенко О.С., Полуэктова Е.А., Румянцев В.Г., Тимербулатов В.М., Чашкова Е.Ю., Шапина М.В., Шептулин А.А., Шифрин О.С., Зольникова О.Ю., Барановский А.Ю., Корочанская Н.В., Маммаев С.Н., Алексеева О.П., Хлынов И.Б., Цуканов В.В., Алексеенко С.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ивашкин В.Т., Шелыгин Ю.А., Баранская Е.К., Ачкасов С.И., Белоус С.С., Белоусова Е.А., Бениашвиили А.Г., Васильев С.В., Григорьев Е.Г., Костенко Н.В., Москалев А.И., Кашников В.Н., Лоранская И.Д., Ляшенко О.С., Полуэктова Е.А., Румянцев В.Г., Тимербулатов В.М., Чашкова Е.Ю., Шапина М.В., Шептулин А.А., Шифрин О.С., Зольникова О.Ю., Барановский А.Ю., Корочанская Н.В., Маммаев С.Н., Алексеева О.П., Хлынов И.Б., Цуканов В.В., Алексеенко С.А.</copyright-holder><copyright-holder xml:lang="en">Ivashkin V.T., Shelygin Y.A., Baranskaya E.K., Achkasov S.I., Belous S.S., Belousova E.A., Beniashviili A.G., Vasiliev S.V., Grigoriev E.G., Kostenko N.V., Moskalev A.I., Kashnikov V.N., Loranskaya I.D., Lyashenko O.S., Poluektova E.A., Rumyantsev V.G., Timerbulatov V.M., Chashkova E.Y., Shapina M.V., Sheptulin A.A., Shifrin O.S., Zolnikova O.Y., Baranovsky A.Y., Korochanskaya N.V., Mammaev S.N., Alekseeva O.P., Khlynov I.B., Tsukanov V.V., Alekseenko S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1706">https://www.ruproctology.com/jour/article/view/1706</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">El Serag HB, Olden K, Bjorkman D, El Serag HB, et al. 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