gnckКолопроктологияKoloproktologia2073-75562686-7303Russian Association of Coloproctology10.33878/2073-7556-2020-19-4-131-149gnck-1594Research ArticleОБЗОРЫ ЛИТЕРАТУРЫ И МЕТААНАЛИЗLITERATURE REVIEWS AND METAANALYSISДИАГНОСТИКА, ЛЕЧЕНИЕ И ПРОГНОЗ У ПАЦИЕНТОВ С КАНЦЕРОМАТОЗОМ БРЮШИНЫ ПРИ КОЛОРЕКТАЛЬНОМ РАКЕ (обзор литературы)DIAGNOSTICS, TREATMENT AND PROGNOSIS IN PATIENTS WITH COLORECTAL CANCER AND PERITONEAL CARCINOMATOSIS (review)ФедянинМ. Ю.FedyaninM. Yu.

д.м.н., с.н.с., Доцент кафедры онкологи и гематологии ФНМО РУДН   

SPINкод: 4381-5628 ул. Миклухо-Маклая, д.21, корп.3, Москва, 117198, Россия

тел. +74993441900

medical oncologistin; assistant professor in Peoples' Friendship University of Russia

SPIN-код: 4381-5628 Miklukho-Maklaya str., 21-3, Moscow, 117198, Russia 

fedianinmu@mail.ruТрякинА. А.TryakinA. A.Тер-ОванесовМ. Д.Ter-OvanesovM. D.ТюляндинС. А.TyulyandinS. A.Онкологическое отделение лекарственного лечения (химиотерапевтического) №2 ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава РоссииРоссияOncological department of chemotherapy #2 in Federal State Budgetary Institution «N.N.Blokhin National Medical Research Center of Oncology» of the Ministry of Health of the Russian FederationRussian FederationОнкологическое отделение лекарственного лечения (химиотерапевтического) №2 ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава РоссииРоссияOncological department of chemotherapy #2 in Federal State Budgetary Institution «N.N.Blokhin National Medical Research Center of Oncology» of the Ministry of Health of the Russian FederationRussian Federation202021122020194131149Copyright © Федянин М.Ю., Трякин А.А., Тер-Ованесов М.Д., Тюляндин С.А., 20202020Федянин М.Ю., Трякин А.А., Тер-Ованесов М.Д., Тюляндин С.А.Fedyanin M.Y., Tryakin A.A., Ter-Ovanesov M.D., Tyulyandin S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ruproctology.com/jour/article/view/1594

Изолированное поражение метастазами брюшины при раке толстой кишки встречается у 1,8% пациентов. Данный тип опухолей характеризуется определенными фенотипическими и молекулярно-генетическими особенностями, что определяет особенности течения заболевания и, соответственно, выбор лечения методов  больных. В настоящем обзоре литературы наряду с описанием основных положений патогенеза заболевания рассмотрены чувствительность и специфичность различных методов диагностики поражения брюшины при раке толстой кишки, выбора системной терапии, необходимости выполнения  хирургического удаления метастазов и проведения внутриперитонеальной гипертермической химиоперфузии.

Isolated colorectal peritoneal metastases occur in 1.8% of patients. This type of tumor is characterized by certain phenotypic and molecular genetic characteristics, which determines the choice of specific treatment options. In this literature review, along with a description of the main principles of the pathogenesis of the disease, the sensitivity and specificity of various diagnostic methods for colorectal peritoneal lesions, the choice of systemic therapy, the need to perform peritonectomy and Intraperitoneal hyperthermic chemoperfusionare considered.

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The authors declare that there are no conflicts of interest present.