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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2020-19-3-97-112</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1589</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>МЕЗЕНХИМАЛЬНЫЕ ОПУХОЛИ ТОЛСТОЙ КИШКИ: ДИАГНОСТИКА, ЛЕЧЕНИЕ, ПРОГНОЗ (клинический случай и обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>MESENCHYMAL TUMORS OF THE COLON AND RECTUM: DIAGNOSIS, TREATMENT, PROGNOSIS (case report and review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Майновская</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mainovskaya</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Olga A. Mainovskaya</p><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Mikhail A. Tarasov</p><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Ekaterina M. Romanova</p><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернышов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernyshov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чернышов Станислав Викторович</p><p>ул. Саляма Адиля, д. 2, г. Москва, 123423</p></bio><bio xml:lang="en"><p>Stanislav V. Chernyshov</p><p>Salyama Adilya str., 2, Moscow, 123423</p></bio><email xlink:type="simple">stchernyshov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ колопроктологии имени А.Н. Рыжих» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryzhikh National Medical Research Center of Coloproctology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>21</day><month>09</month><year>2020</year></pub-date><volume>19</volume><issue>3</issue><fpage>97</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Майновская О.А., Тарасов М.А., Романова Е.М., Чернышов С.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Майновская О.А., Тарасов М.А., Романова Е.М., Чернышов С.В.</copyright-holder><copyright-holder xml:lang="en">Mainovskaya O.A., Tarasov M.A., Romanova E.M., Chernyshov S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1589">https://www.ruproctology.com/jour/article/view/1589</self-uri><abstract><p>Мезенхимальные опухоли толстой кишки встречаются крайне редко и не имеют специфической клинической картины, их диагностика и стадирование вызывает определённые трудности. Различные типы мезенхимальных опухолей отличаются прогнозом и выбором тактики лечения. Это объясняет важность дифференциальной диагностики этих новообразований между собой и опухолями-производными других эмбриональных структур.</p><p>В статье описан клинический случай редкой мезенхимальной опухоли толстой кишки, а также тактика ведения пациента.</p></abstract><trans-abstract xml:lang="en"><p>Mesenchymal tumors of the colon and rectum are extremely rare and do not have specific clinical manifestations, their diagnosis and staging cause certain difficulties.</p><p>Different types of mesenchymal tumors differ in prognosis and choice of the treatment. It explains the importance of differential diagnosis of these neoplasms among themselves and tumors-derivatives of other embryonic structures.</p><p>The article describes the clinical case of a rare mesenchymal tumor and management of the patient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мезенхимальные опухоли толстой кишки</kwd><kwd>гастроинтестинальная стромальная опухоль</kwd><kwd>ГИСТ</kwd><kwd>лейомиома</kwd><kwd>лейомиосаркома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mesenchymal tumor</kwd><kwd>gastrointestinal stromal tumor (GIST)</kwd><kwd>leiomyoma</kwd><kwd>leiomyosarcoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sherri L, Stewart et al. A Population-Based Study of Colorectal Cancer Histology in the United States, 1998-2001. Colorectal Cancer Histology. 2006:1128-1141. doi:10.1002/cncr.22010.</mixed-citation><mixed-citation xml:lang="en">Sherri L, Stewart et al. A Population-Based Study of Colorectal Cancer Histology in the United States, 1998-2001. Colorectal Cancer Histology. 2006:1128-1141. doi:10.1002/cncr.22010.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Devriendt S, Leman G, Vanrykel F. Primary leiomyosarcoma of the colon: a case report and review of the literature. Acta Chirurgica Belgica. 2019:1-4. doi:10.1080/00015458.2019.1589185.</mixed-citation><mixed-citation xml:lang="en">Devriendt S, Leman G, Vanrykel F. Primary leiomyosarcoma of the colon: a case report and review of the literature. Acta Chirurgica Belgica. 2019:1-4. doi:10.1080/00015458.2019.1589185.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Maron DJ. Carcinoids, GISTs, and Lymphomas of the Colon and Rectum. In: Steele S., Hull T., Hyman N., Maykel J., Read T., Whitlow C. The ASCRS Manual of Colon and Rectal Surgery. Springer, Cham. 2019.</mixed-citation><mixed-citation xml:lang="en">Maron DJ. Carcinoids, GISTs, and Lymphomas of the Colon and Rectum. In: Steele S., Hull T., Hyman N., Maykel J., Read T., Whitlow C. The ASCRS Manual of Colon and Rectal Surgery. Springer, Cham. 2019.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ma G, Murphy J, Martinez M. et al. Epidemiology of gastrointestinal stromal tumors in the era of histology codes: results of a population-based study. Cancer Epidemiol Biomarkers Prev. 2015;24:298-302. doi:10.1158/1055-9965.EPI-14-1002.</mixed-citation><mixed-citation xml:lang="en">Ma G, Murphy J, Martinez M. et al. Epidemiology of gastrointestinal stromal tumors in the era of histology codes: results of a population-based study. Cancer Epidemiol Biomarkers Prev. 2015;24:298-302. doi:10.1158/1055-9965.EPI-14-1002.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Никулин М.П., Стилиди И.С. Гастроинтестинальные стромальные опухоли (ГИСО). Эпидемиология, диагностика, современные подходы к лечению. Современная онкология. Экстра-выпуск. 2007, с. 3-50.</mixed-citation><mixed-citation xml:lang="en">Nikulin M.P., Sitilidi I.S. Gastointestinal stromal tumors (GIST). Epidemiology, diagnostic, modern treatment approaches. Modern oncology. Extra-edition. 2007; pp. 3-50. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ассоциация онкологов России, Российское общество клинической онкологии. Клинические рекомендации «Гастроинтестинальные стромальные опухоли». 2018.</mixed-citation><mixed-citation xml:lang="en">Association of Oncologists of Russia, Russian society of clinical oncology. Clinical guidance «Gastrointestinal stromal tumors». 2018. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Мазуренко Н.Н., Цыганова И.В. Молекулярно-генетические особенности и маркеры гастроинтестинальных стромальных опухолей. Успехи молекулярной онкологии. 2015; № 2, с. 29-37. doi: 10.17650/2313-805X.2015.2.2.29-40.</mixed-citation><mixed-citation xml:lang="en">Mazurenko N.N., Tsyganova I.V. Molecular features and genetic markers of gastrointestinal stromal tumors. Success of molecular oncology. 2015; no. 2, pp. 29-37. doi:10.17650/2313805X.2015.2.2.29-40. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Халиков Д.Д., Ахметзянов Ф.Ш., Петров С.В. Клиникоморфологическая характеристика гастроинтестинальных стромальных опухолей. Архив патологии. 2017; № 79(4), с. 48-55. doi:10.17116/patol201779448-55.</mixed-citation><mixed-citation xml:lang="en">Khalikov D.D., Akhmetzyanov F.Sh., Petrov S.V. Clinical and morphological characteristics of gastrointestinal stromal tumors. Archive of pathology. 2017; no. 79(4), pp. 48-55. doi:10.17116/patol201779448-55. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Miettinen M, Furlong M, Sarlomo-Rikala M. et al. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J SurgPathol. 2001;25(9):1121-1133. doi: 10.1097/00000478-200109000-00002.</mixed-citation><mixed-citation xml:lang="en">Miettinen M, Furlong M, Sarlomo-Rikala M. et al. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J SurgPathol. 2001;25(9):1121-1133. doi: 10.1097/00000478-200109000-00002.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Emile J, Brahimi S, Coindre J. et al. Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective populationbased study differ from those of advanced GISTs. Med Oncol. 2012;29(3):1765-1772. doi: 10.1007/s12032-011-0074-y.</mixed-citation><mixed-citation xml:lang="en">Emile J, Brahimi S, Coindre J. et al. Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective populationbased study differ from those of advanced GISTs. Med Oncol. 2012;29(3):1765-1772. doi: 10.1007/s12032-011-0074-y.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Killian J, Miettinen M, Walker R. et al. Recurrent epimutation of SDHC in gastrointestinal stromal tumors. Sci Transl Med. 2014;24;6(268):268-277. doi: 10.1126/scitranslmed.3009961.</mixed-citation><mixed-citation xml:lang="en">Killian J, Miettinen M, Walker R. et al. Recurrent epimutation of SDHC in gastrointestinal stromal tumors. Sci Transl Med. 2014;24;6(268):268-277. doi: 10.1126/scitranslmed.3009961.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lindberg M. Gastrointestinal stromal tumor. Diagnostic pathology. Soft tissue tumors 2nd edition. Elsevier, 2016:734-749.</mixed-citation><mixed-citation xml:lang="en">Lindberg M. Gastrointestinal stromal tumor. Diagnostic pathology. Soft tissue tumors 2nd edition. Elsevier, 2016:734-749.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Koliaraki V, Pallangyo CK, Greten FR. et al. Mesenchymal Cells in Colon Cancer. Gastroenterology. 2017:152(5):964-979. doi: 10.1053/j.gastro.2016.11.049.</mixed-citation><mixed-citation xml:lang="en">Koliaraki V, Pallangyo CK, Greten FR. et al. Mesenchymal Cells in Colon Cancer. Gastroenterology. 2017:152(5):964-979. doi:10.1053/j.gastro.2016.11.049.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nishida T, Blay J-Y, Hirota S. et al. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines. Gastric Cancer. 2015;19(1):3-14. doi: 10.1007/s10120-015-0526-8.</mixed-citation><mixed-citation xml:lang="en">Nishida T, Blay J-Y, Hirota S. et al. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines. Gastric Cancer. 2015;19(1):3-14. doi: 10.1007/s10120-015-0526-8.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Classification of Tumors Editorial Board. Digestive system Tumours. 5th. ed. Lyon (France): International agency for Research on Cancer; 2019.</mixed-citation><mixed-citation xml:lang="en">WHO Classification of Tumors Editorial Board. Digestive system Tumours. 5th. ed. Lyon (France): International agency for Research on Cancer; 2019.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lasota J, Miettinen M. Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology. 2008;53:245-266. doi: 10.1111/j.13652559.2008.02977.x.</mixed-citation><mixed-citation xml:lang="en">Lasota J, Miettinen M. Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology. 2008;53:245-266. doi: 10.1111/j.13652559.2008.02977.x.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Joensuu H, Vehtari A, Riihimaki J. et al. Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts. Lancet Oncol. 2012;13:265-274. doi: 10.1016/S1470-2045(11)70299-6.</mixed-citation><mixed-citation xml:lang="en">Joensuu H, Vehtari A, Riihimaki J. et al. Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts. Lancet Oncol. 2012;13:265-274. doi: 10.1016/S1470-2045(11)70299-6.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Miettinen M, Lasota J. Gastrointestinal Stromal Tumors. Review on Morphology, Molecular Pathology, Prognosis, and Differential Diagnosis. Arch Pathol Lab Med. 2006;130:1466-1476. doi: 10.1043/1543-2165(2006)130[1466:GSTROM]2.0.CO;2.</mixed-citation><mixed-citation xml:lang="en">Miettinen M, Lasota J. Gastrointestinal Stromal Tumors. Review on Morphology, Molecular Pathology, Prognosis, and Differential Diagnosis. Arch Pathol Lab Med. 2006;130:1466-1476. doi: 10.1043/1543-2165(2006)130[1466:GSTROM]2.0.CO;2.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Heikki J. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Human pathology. 2008;39:14111419. doi:10.1016/j.humpath.2008.06.025.</mixed-citation><mixed-citation xml:lang="en">Heikki J. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Human pathology. 2008;39:14111419. doi:10.1016/j.humpath.2008.06.025.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">McCarter MD, Antonescu CR, Ballman KV. et al. American College of Surgeons Oncology Group (ACOSOG) Intergroup Adjuvant Gist Study Team. Microscopically positive margins for primary gastrointestinal stromal tumors: analysis of risk factors and tumor recurrence. J Am Coll Surg. 2012;215:53-59. doi:10.1016/j.jamcollsurg.2012.05.008.</mixed-citation><mixed-citation xml:lang="en">McCarter MD, Antonescu CR, Ballman KV. et al. American College of Surgeons Oncology Group (ACOSOG) Intergroup Adjuvant Gist Study Team. Microscopically positive margins for primary gastrointestinal stromal tumors: analysis of risk factors and tumor recurrence. J Am Coll Surg. 2012;215:53-59. doi:10.1016/j.jamcollsurg.2012.05.008.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Corless CL, Ballman KV, Antonescu CR. et al. Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. J Clin Oncol. 2014;32:1563-1570. doi:10.1200/JCO.2013.51.2046.</mixed-citation><mixed-citation xml:lang="en">Corless CL, Ballman KV, Antonescu CR. et al. Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. J Clin Oncol. 2014;32:1563-1570. doi:10.1200/JCO.2013.51.2046.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">He LJ, Wang BS, Chen CC. Smooth muscle tumors of the digestive tract: report of 160 cases. Br J Surg. 1988;75:184-186. doi: 10.1002/bjs.1800750233.</mixed-citation><mixed-citation xml:lang="en">He LJ, Wang BS, Chen CC. Smooth muscle tumors of the digestive tract: report of 160 cases. Br J Surg. 1988;75:184-186. doi: 10.1002/bjs.1800750233.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Kusminsky RE, Bailey W. Leiomyomas of the rectum and anal canal: report of 6 cases and review of the literature. Dis Colon Rectum. 1977;20:580-599. doi:10.1007/BF02586622.</mixed-citation><mixed-citation xml:lang="en">Kusminsky RE, Bailey W. Leiomyomas of the rectum and anal canal: report of 6 cases and review of the literature. Dis Colon Rectum. 1977;20:580-599. doi:10.1007/BF02586622.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Suzuki A, Fukuda S, Tomita S. et al. An unusual case of colonic leiomyosarcoma presenting with fever. Signiﬁcant uptake of radioactivity of gallium-67 in the tumor. Gastroenterol Jpn. 1984;19:486-492. doi: 10.1007/BF02807262.</mixed-citation><mixed-citation xml:lang="en">Suzuki A, Fukuda S, Tomita S. et al. An unusual case of colonic leiomyosarcoma presenting with fever. Signiﬁcant uptake of radioactivity of gallium-67 in the tumor. Gastroenterol Jpn. 1984;19:486-492. doi: 10.1007/BF02807262.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Lindberg M. Gastrointestinal Smooth Muscle Neoplasms. Diagnostic pathology. Soft tissue tumors 2nd edition. Elsevier 2016:752-755.</mixed-citation><mixed-citation xml:lang="en">Lindberg M. Gastrointestinal Smooth Muscle Neoplasms. Diagnostic pathology. Soft tissue tumors 2nd edition. Elsevier 2016:752-755.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Coindre JM. Grading of soft tissue sarcomas: review and update. Arch Pathol Lab Med. 2006;130(10):1448-53. doi: 10.1043/1543-2165(2006)130[1448:GOSTSR]2.0.CO;2.</mixed-citation><mixed-citation xml:lang="en">Coindre JM. Grading of soft tissue sarcomas: review and update. Arch Pathol Lab Med. 2006;130(10):1448-53. doi: 10.1043/1543-2165(2006)130[1448:GOSTSR]2.0.CO;2.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Nuessle WR, Magill TR. Leiomyosarcoma of the transverse colon. Report of a case with discussion. Dis Colon Rectum. 1990;33:323-326. doi: 10.1007/BF02055477.</mixed-citation><mixed-citation xml:lang="en">Nuessle WR, Magill TR. Leiomyosarcoma of the transverse colon. Report of a case with discussion. Dis Colon Rectum. 1990;33:323-326. doi: 10.1007/BF02055477.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Vorobyov G.I., Odaryuk T.S., Shelygin Yu.A. et al. Surgical Treatment of Benign, Myomatous Rectal Tumors. Dis Colon Rectum. 1992;35(4):328-331. doi:10.1007/BF02048109.</mixed-citation><mixed-citation xml:lang="en">Vorobyov G.I., Odaryuk T.S., Shelygin Yu.A. et al. Surgical Treatment of Benign, Myomatous Rectal Tumors. Dis Colon Rectum. 1992;35(4):328-331. doi:10.1007/BF02048109.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Yang J. Primary leiomyosarcoma in the colon: A case report. Medicine (Baltimore).2018;97(7): e9923. doi: 10.1097/MD.0000000000009923.</mixed-citation><mixed-citation xml:lang="en">Yang J. Primary leiomyosarcoma in the colon: A case report. Medicine (Baltimore).2018;97(7): e9923. doi: 10.1097/MD.0000000000009923.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Чеснокова Н.П., Невважай Т.А., Понукалина Е.В. и соавт. Лейкемоидные реакции: классификация, этиология, патогенез, принципиальные отличия от лейкозов. Международный журнал экспериментального образования. 2015; № 7, с. 186-188.</mixed-citation><mixed-citation xml:lang="en">Chesnokova N.P., Nevvazhai T.A., Ponukalina E.V. et al.Leukemoid reactions: classifications, etiology, pathogenesis, fundamental differences from leukemia. International journal of experimental education. 2015; no. 7, pp. 186-188. (in Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
