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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gnck</journal-id><journal-title-group><journal-title xml:lang="ru">Колопроктология</journal-title><trans-title-group xml:lang="en"><trans-title>Koloproktologia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7556</issn><issn pub-type="epub">2686-7303</issn><publisher><publisher-name>Russian Association of Coloproctology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33878/2073-7556-2019-18-4-130-133</article-id><article-id custom-type="elpub" pub-id-type="custom">gnck-1523</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>СВЕРХТЯЖЕЛАЯ ФОРМА ЯЗВЕННОГО КОЛИТА (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>ACUTE SEVERE ULCERATIVE COLITIS (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пак</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Pak</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаева</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaeva</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коротаева Наталья Сергеевна</p><p>Иркутская областная клиническая больница</p><p>мкр. Юбилейный, 100, г. Иркутск, 664049</p></bio><bio xml:lang="en"/><email xlink:type="simple">korotaeva.natali@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чашкова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chashkova</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Желтовская</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zheltovskaya</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макеева</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Makeeva</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутский государственный медицинский университет;&#13;
ГБУЗ Иркутская ордена «Знак почета» областная клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical University;&#13;
Irkutsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»;&#13;
ГБУЗ Иркутская ордена «Знак почета» областная клиническая больница</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Irkutsk Scientific Center of Surgery and Traumatology;&#13;
Irkutsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Иркутская ордена «Знак почета» областная клиническая больница</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Irkutsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Irkutsk Scientific Center of Surgery and Traumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>21</day><month>12</month><year>2019</year></pub-date><volume>18</volume><issue>4</issue><fpage>130</fpage><lpage>133</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пак В.Е., Коротаева Н.С., Чашкова Е.Ю., Желтовская А.А., Макеева И.Е., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Пак В.Е., Коротаева Н.С., Чашкова Е.Ю., Желтовская А.А., Макеева И.Е.</copyright-holder><copyright-holder xml:lang="en">Pak V.E., Korotaeva N.S., Chashkova E.Y., Zheltovskaya A.A., Makeeva I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ruproctology.com/jour/article/view/1523">https://www.ruproctology.com/jour/article/view/1523</self-uri><abstract><p>Представлено клиническое наблюдение дебюта сверхтяжелой (фульминантной) формы язвенного колита у молодого, ранее практически здорового пациента. Диагноз установлен при поступлении в инфекционное отделений районной больницы, начато этиопатогенетическое лечение. Неэффективно. Переведен в специализированное отделение областной клинической больницы в тяжелом состоянии с метаболическими и волемическими нарушениями, анемией, тромбоцитопенией, синдромом системной воспалительной реакции. Несмотря на интенсивную терапию, состояние ухудшалось, рецидивировало массивное кишечное кровотечение. По неот-ложным показаниям выполнена колпроктэктомия. Илеостома по Бруку. При патоморфологическом исследовании диагноз язвенного колита подтвержден – воспаление высокой степени активности с вовлечением подслизистого и мышечного слоев кишки с множественными крипт-абсцессами. На 26-е сутки выписан в удовлетворительном состоянии на амбулаторное лечение. Осмотрен через 3,5 года. Самочувствие удовлетворительное. Режим питания и характер пищи без ограничений. Работает по специальности.</p></abstract><trans-abstract xml:lang="en"><p>The case report of the onset of acute severe ulcerative colitis (ASUC) in a young, previously healthy patient. The UC was revealed department of the infectious disease in general hospital, a proper conservative treatment was started but was ineffective. The patient was taken to the colorectal surgery unit of the tertiary referral center. His status was very poor including metabolic changes and dehydration, anemia, thrombocytopenia, systemic inflammatory response syndrome. Despite intensive therapy, the condition impaired and massive intestinal bleeding recurred. Urgent colproctectomy with end ileostomy was performed. Pathomorphological study verified the diagnosis of ulcerative colitis – highly active inflammation involving the submucosal and muscular layers of the intestine with multiple crypt abscesses. The patient was discharged 2 days after surgery. Follow-up was 3.5 years, patient in good condition without restrictions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>язвенный колит</kwd><kwd>сверхтяжелая форма</kwd><kwd>хирургический сепсис</kwd><kwd>массивное кровотечение</kwd><kwd>неотложная колопроктэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ulcerative colitis</kwd><kwd>super severe course</kwd><kwd>surgical sepsis</kwd><kwd>massive bleeding</kwd><kwd>urgent coloproctology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Шелыгин Ю.А., Халиф И.Л. и соавт. Клинические рекомендации Российской гастроэнтерологической ассоциации и ассоциации колопроктологов России по диагностике и лечению язвенного колита. Колопроктология. 2017; № 1(59), с. 6-30.</mixed-citation><mixed-citation xml:lang="en">Ivashkin V.T., Shelygin Yu.A., Khalif I.L. еt al. 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